SCHEMBL4524708

SCHEMBL4524708

OCCOc1ccc(/C=C/CCCOc2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
RECQL P46063 1/20 0.59
PPARA Q07869 3/20 0.50
GAA P10253 1/20 0.47
RELA Q04206 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
PPARD Q03181 1/20 0.46
CHRNA7 P36544 8/20 0.46
KCNA3 P22001 1/20 0.46
CHRNB4 P30926 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNA10 Q9GZZ6 1/20 0.45
CHRNA9 Q9UGM1 1/20 0.45
S1PR1 P21453 1/20 0.44
S1PR3 Q99500 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4513923 1.00 ALDH1A1 (0.59) ALDH1A1RECQLPPARAGAARELA
SCHEMBL4513918 1.00 ALDH1A1 (0.59) ALDH1A1RECQLPPARAGAARELA
SCHEMBL4508132 0.89 PPARA (0.48) ALDH1A1RECQLPPARARELAHDAC1
SCHEMBL4508128 0.89 PPARA (0.48) ALDH1A1RECQLPPARARELAHDAC1
SCHEMBL4508135 0.89 PPARA (0.48) ALDH1A1RECQLPPARARELAHDAC1
SCHEMBL6171091 0.86 DRD2 (0.51) PPARARELAPPARDCHRNA7KCNA3
SCHEMBL4510807 0.85 LTA4H (0.52) ALDH1A1RECQLPPARAHDAC1HDAC2
SCHEMBL4510808 0.85 LTA4H (0.52) ALDH1A1RECQLPPARAHDAC1HDAC2
SCHEMBL4526042 0.85 LTA4H (0.52) ALDH1A1RECQLPPARAHDAC1HDAC2
SCHEMBL4525962 0.84 RELA (0.47) ALDH1A1PPARARELAPPARDCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7498460-B2 Isophthalic acid derivatives BAYER HEALTHCARE AG (DE) 2009-03-03 US disclosed
EP-1572628-B1 ISOPHTALIC ACID DERIVATIVES BAYER HEALTHCARE AG (DE) 2007-07-25 EP disclosed
US-20060154912-A1 Isophtalic acid derivatives BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2006-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060154912-A1 Isophtalic acid derivatives VHL, FABP3, CPT1A ALDH1A1 60/4885RECQL 2021/4885PPARA 42/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.