SCHEMBL45260

SCHEMBL45260

CC(C)(C)c1cc(C(C)(C)Cl)cc(C(C)(C)Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.52
GABRB2 P47870 1/20 0.52
POLB P06746 1/20 0.48
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HTR1D P28221 2/20 0.36
RXRB P28702 5/20 0.35
RXRA P19793 4/20 0.35
RXRG P48443 3/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.33
TYR P14679 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTR1B P28222 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7763323 1.00 GABRA1 (0.52) GABRA1GABRB2POLBGAAMAPT
SCHEMBL45290 0.90 GABRA1 (0.38) GABRA1GABRB2POLBTSHR
SCHEMBL3683051 0.85 GABRA1 (0.41) GABRA1GABRB2POLBGAAMAPT
SCHEMBL93161 0.83 GABRA1 (0.69) GABRA1GABRB2POLBGAAMAPT
SCHEMBL14347036 0.81 RXRB (0.35) GABRA1GABRB2POLBGAAMAPT
SCHEMBL10394690 0.79 GABRA1 (0.65) GABRA1GABRB2POLBGAAMAPT
SCHEMBL10415675 0.79 GABRA1 (0.65) GABRA1GABRB2POLBGAAMAPT
SCHEMBL7203013 0.78 HDAC8 (0.47) GABRA1GABRB2GAAMAPTRXRB
SCHEMBL10537131 0.76 GABRA1 (0.42) GABRA1GABRB2POLBGAAMAPT
SCHEMBL10183607 0.75 GABRA1 (0.52) GABRA1GABRB2POLBGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795247-B2 Polyolefin dispersants and methods of making and using thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-24 US claimed
CN-111285948-B Method for preparing halogenated polyisobutenyl special elastomer by one-step method and application 北京石油化工学院 2022-12-09 CN claimed
CN-112608402-B Styrene block copolymer and preparation method thereof 北京化工大学 2022-02-11 CN claimed
US-20210189030-A1 Polyolefin Dispersants and Methods of Making and Using Thereof UNIVERSITY OF SOUTHERN MISSISSIPPI 2021-06-24 US claimed
US-20190284314-A1 Polyolefin Dispersants and Methods of Making and Using Thereof CHEVRON ORONITE COMPANY LLC. 2019-09-19 US claimed
EP-2387592-B1 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIV OF SOUTHERN MISSISSIPPI (US) 2018-08-29 EP claimed
US-9650449-B2 Functionalization of polyolefins with phenoxy derivatives THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2017-05-16 US claimed
EP-2459599-B1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS UNIV SOUTHERN MISSISSIPPI (US) 2016-07-20 EP claimed
EP-2284203-B1 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE CO (US) 2015-03-04 EP claimed
US-8895672-B2 Production of vinylidene-terminated and sulfide-terminated telechelic polyolefins via quenching with disulfides CHEVRON ORONITE COMPANY LLC (US) 2014-11-25 US claimed
WO-2004058829-A1 POLYMERIZATION PROCESSES EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2004-07-15 WO claimed
US-20040054103-A1 Process for polymerizing cationically polymerizable monomers WEBB ROBERT N (US) 2004-03-18 US claimed
EP-1358230-A1 PROCESS FOR POLYMERIZING CATIONICALLY POLYMERIZABLE MONOMERS ExxonMobil Chemical Patents Inc. (US) 2003-11-05 EP claimed
US-6620898-B2 In the presence of a catalyst composition of a lewis acid based on a metal and an initiator alkyl, alkenyl or aryl substituted with a carboxy, halo, hydroxy or alkoxy EXXONMOBIL CHEMICAL PATENTS INC. 2003-09-16 US claimed
US-20020173612-A1 Production of polyisobutylene copolymers WEBB ROBERT N (US) 2002-11-21 US claimed
EP-1237950-A1 PRODUCTION OF ISOBUTYLENE COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 2002-09-11 EP claimed
US-6444768-B1 CONTINUOUS SLURRYING POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. 2002-09-03 US claimed
WO-2002050141-A1 PROCESS FOR POLYMERIZING CATIONICALLY POLYMERIZABLE MONOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-06-27 WO claimed
WO-2001036498-A1 PRODUCTION OF ISOBUTYLENE COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO claimed
US-5403803-A Polymerization catalyst for alpha-olefins EXXON CHEMICAL PATENTS INC. (US) 1995-04-04 US claimed