SCHEMBL45290

SCHEMBL45290

CC(C)(Cl)c1cc(C(C)(C)Cl)cc(C(C)(C)Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
TSHR P16473 1/20 0.36
POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14347036 0.90 RXRB (0.35) GABRA1GABRB2POLB
SCHEMBL45260 0.90 GABRA1 (0.52) GABRA1GABRB2TSHRPOLB
SCHEMBL7763323 0.90 GABRA1 (0.52) GABRA1GABRB2TSHRPOLB
SCHEMBL45022 0.81 ESR1 (0.44) TSHR
SCHEMBL9403849 0.81 TSHR (0.47) TSHR
SCHEMBL9175418 0.78 ALDH1A1 (0.43) TSHR
SCHEMBL13705007 0.78 ALDH1A1 (0.32) TSHR
SCHEMBL45199 0.77 MEN1 (0.41) TSHR
SCHEMBL3683051 0.77 GABRA1 (0.41) GABRA1GABRB2POLB
SCHEMBL13908885 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795247-B2 Polyolefin dispersants and methods of making and using thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-24 US claimed
US-20210189030-A1 Polyolefin Dispersants and Methods of Making and Using Thereof UNIVERSITY OF SOUTHERN MISSISSIPPI 2021-06-24 US claimed
US-20190284314-A1 Polyolefin Dispersants and Methods of Making and Using Thereof CHEVRON ORONITE COMPANY LLC. 2019-09-19 US claimed
EP-2387592-B1 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIV OF SOUTHERN MISSISSIPPI (US) 2018-08-29 EP claimed
US-9650449-B2 Functionalization of polyolefins with phenoxy derivatives THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2017-05-16 US claimed
CN-106146707-A Preparation method of halogenated polymer 中国石油化工股份有限公司 2016-11-23 CN claimed
CN-106146706-A Cationic polymerization method 中国石油化工股份有限公司 2016-11-23 CN claimed
CN-106146709-A Cationic polymerization method 中国石油化工股份有限公司 2016-11-23 CN claimed
CN-106146705-A Preparation method of halogenated polymer 中国石油化工股份有限公司 2016-11-23 CN claimed
US-20160311952-A1 Crosslinked Polyolefins for Biomedical Applications and Method of Making Same INNOLENE LLC (US) 2016-10-27 US claimed
WO-2001036498-A1 PRODUCTION OF ISOBUTYLENE COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO claimed
EP-0609737-B1 Process for producing a halogenated butyl rubber BAYER INC (CA) 2000-06-07 EP claimed
US-5473029-A Copolymerization of isobutylene with a conjugated diolefin bearing an allylic halide in the presence of an initiator and a lewis acid BAYER RUBBER INC. (CA) 1995-12-05 US claimed
EP-0609737-A2 Process for producing a halogenated butyl rubber BAYER RUBBER INC. (CA) 1994-08-10 EP claimed
US-RE34640-E Polymerizing isobutylene, adding monomer to make block polymer; metal halide, initiator and electron pair doner solvent UNIVERSITY OF AKRON (US) 1994-06-14 US claimed
EP-0341012-B1 UNIFORM MOLECULAR WEIGHT POLYMERS EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1992-12-30 EP claimed
WO-1991011468-A1 NEW THERMOPLASTIC ELASTOMERS THE UNIVERSITY OF AKRON (US) 1991-08-08 WO claimed
US-4946899-A CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE THE UNIVERSITY OF AKRON (US) 1990-08-07 US claimed
EP-0341012-A2 Uniform molecular weight polymers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-11-08 EP claimed
US-4399073-A FROM THE HALIDE AND ALKALI METAL CYANATE, WATER AMERICAN CYANAMID COMPANY (US) 1983-08-16 US claimed