Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | RXRB | P28702 | 5/20 | 0.35 |
| ▸ | RXRA | P19793 | 4/20 | 0.35 |
| ▸ | RXRG | P48443 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45260 | 1.00 | GABRA1 (0.52) | GABRA1GABRB2POLBGAAMAPT | |
| SCHEMBL45290 | 0.90 | GABRA1 (0.38) | GABRA1GABRB2POLBTSHR | |
| SCHEMBL3683051 | 0.85 | GABRA1 (0.41) | GABRA1GABRB2POLBGAAMAPT | |
| SCHEMBL93161 | 0.83 | GABRA1 (0.69) | GABRA1GABRB2POLBGAAMAPT | |
| SCHEMBL14347036 | 0.81 | RXRB (0.35) | GABRA1GABRB2POLBGAAMAPT | |
| SCHEMBL10394690 | 0.79 | GABRA1 (0.65) | GABRA1GABRB2POLBGAAMAPT | |
| SCHEMBL10415675 | 0.79 | GABRA1 (0.65) | GABRA1GABRB2POLBGAAMAPT | |
| SCHEMBL7203013 | 0.78 | HDAC8 (0.47) | GABRA1GABRB2GAAMAPTRXRB | |
| SCHEMBL10537131 | 0.76 | GABRA1 (0.42) | GABRA1GABRB2POLBGAAMAPT | |
| SCHEMBL10183607 | 0.75 | GABRA1 (0.52) | GABRA1GABRB2POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675153-B1 | Process for the preparation of star-shaped polymers | SHELL INT RESEARCH (NL) | 2001-06-13 | — | — | EP | claimed |
| US-5458796-A | Synthesis of polyisobutylene star-branched polymers via living carbocationic polymerization | SHELL OIL COMPANY (US) | 1995-10-17 | — | — | US | claimed |
| US-9394390-B2 | Coumarin-functionalized polyolefin and associated cyclodimerization products, preparation methods, and electronic devices | THE UNIVERSITY OF MASSACHUSETTS (US) | 2016-07-19 | — | — | US | disclosed |
| US-20160008607-A1 | POLYMERIC FEED-THRU FOR CHRONIC IMPLANTABLE DEVICES | CARDIAC PACEMAKERS, INC. | 2016-01-14 | — | — | US | disclosed |
| US-20150361195-A1 | COUMARIN-FUNCTIONALIZED POLYOLEFIN AND ASSOCIATED CYCLODIMERIZATION PRODUCTS, PREPARATION METHODS, AND ELECTRONIC DEVICES | THE UNIVERSITY OF MASSACHUSETTS | 2015-12-17 | — | — | US | disclosed |
| US-20130190525-A1 | SYNTHETIC METHODS PERTAINING TO TERT-BUTYL-BENZENE-BASED COMPOUNDS | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2013-07-25 | — | — | US | disclosed |
| EP-0675153-B1 | Process for the preparation of star-shaped polymers | SHELL INT RESEARCH (NL) | 2001-06-13 | — | — | EP | disclosed |
| EP-1099717-A2 | Star-shaped polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2001-05-16 | — | — | EP | disclosed |
| US-5458796-A | Synthesis of polyisobutylene star-branched polymers via living carbocationic polymerization | SHELL OIL COMPANY (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0675153-A1 | Star-shaped polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190525-A1 | SYNTHETIC METHODS PERTAINING TO TERT-BUTYL-BENZENE-BASED COMPOUNDS | TERT, HMBS, BET1 | GABRA1 598/4885GABRB2 415/4885POLB 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.