SCHEMBL7203013

SCHEMBL7203013

CC(C)(C)c1cccc(C(C)(C)Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.47
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47
KIF11 P52732 3/20 0.45
ACHE P22303 3/20 0.42
RXRA P19793 2/20 0.40
RXRB P28702 2/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
PGK1 P00558 1/20 0.40
PGK2 P07205 1/20 0.40
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
NPC1 O15118 1/20 0.38
PLA2G1B P04054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45022 0.92 ESR1 (0.44) HDAC8HDAC4HDAC2KIF11ACHE
SCHEMBL129151 0.87 HDAC8 (0.56) HDAC8HDAC4HDAC2KIF11ACHE
Water SCHEMBL29289408 0.84 HDAC8 (0.54) HDAC8HDAC4HDAC2KIF11ACHE
SCHEMBL11662186 0.81 TSHR (0.50) ALDH1A1L3MBTL1TSHR
Nitrogen SCHEMBL28547462 0.79 HDAC8 (0.50) HDAC8HDAC4HDAC2KIF11ACHE
Methoxymethane SCHEMBL28022475 0.79 HDAC8 (0.50) HDAC8HDAC4HDAC2KIF11ACHE
SCHEMBL45260 0.78 GABRA1 (0.52) RXRARXRBALDH1A1HPGDALOX15
SCHEMBL7763323 0.78 GABRA1 (0.52) RXRARXRBALDH1A1HPGDALOX15
SCHEMBL11662449 0.78 ACHE (0.50) KIF11ACHEALDH1A1TDP1NPC1
SCHEMBL11469047 0.78 CYP19A1 (0.43) KIF11ALDH1A1L3MBTL1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111094394-A Polyolefin dispersants and methods of making and using the same 雪佛龙奥伦耐有限责任公司 2020-05-01 CN claimed
WO-2003068832-A1 CUREABLE SILANE FUNCTIONALIZED SEALANT COMPOSITION AND MANUFACTURE OF SAME BRIDGESTONE CORPORATION (JP) 2003-08-21 WO claimed
CN-117957283-A Resin composition and molded article thereof 帝人株式会社 2024-04-30 CN disclosed
CN-111902448-B Poly (ether-carbonate) -based polymer and medical device 美敦力公司 2022-09-30 CN disclosed
CN-108368194-B Method for producing (meth) acryloyl group-terminated polyisobutylene polymer 株式会社钟化 2021-03-19 CN disclosed
US-10882945-B2 Modified polyisobutylene-based polymers, methods of making, and medical devices MEDTRONIC, INC. (US) 2021-01-05 US disclosed
CN-111902448-A Poly (ether-carbonate) -based polymer and medical device 美敦力公司 2020-11-06 CN disclosed
CN-111902449-A Modified polyisobutenyl polymer, method of making, and medical device 美敦力公司 2020-11-06 CN disclosed
CN-111133084-A Polyimide dispersants and methods of making and using the same 雪佛龙奥伦耐有限责任公司 2020-05-08 CN disclosed
CN-111094394-A Polyolefin dispersants and methods of making and using the same 雪佛龙奥伦耐有限责任公司 2020-05-01 CN disclosed
CN-107614555-B Method for producing thermoplastic elastomer and thermoplastic elastomer 株式会社钟化 2020-03-20 CN disclosed
CN-1301301-C Polymer composition containing double salt whose metal components are magnesium and aluminum KANEGAFUCHI CHEMICAL IND (JP) 2007-02-21 CN disclosed
CN-1247732-C Vibration damper composition KANEGAFUCHI CHEMICAL IND (JP) 2006-03-29 CN disclosed
CN-1223617-C Isobutylene block copolymer contg. active silicon group and preparing process thereof KANEGAFUCHI CHEMICAL IND (JP) 2005-10-19 CN disclosed
CN-1681889-A Polymer composition containing double salt whose metal components are magnesium and aluminum KANEGAFUCHI CHEMICAL IND (JP) 2005-10-12 CN disclosed
WO-2003068832-A1 CUREABLE SILANE FUNCTIONALIZED SEALANT COMPOSITION AND MANUFACTURE OF SAME BRIDGESTONE CORPORATION (JP) 2003-08-21 WO disclosed
CN-1422317-A Vibration damper composition KANEGAFUCHI CHEMICAL IND (JP) 2003-06-04 CN disclosed
CN-1420131-A Isobutylene block copolymer contg. active silicon group and preparing process thereof KANEGAFUCHI CHEMICAL IND (JP) 2003-05-28 CN disclosed
CN-1097600-C Alkenyl-containing isobutylene block copolymer and process for producing the same KANEGAFUCHI CHEMICAL IND (JP) 2003-01-01 CN disclosed
CN-1223269-A Alkenyl-containing isobutylene block copolymer and process for producing the same KANEGAFUCHI CHEMICAL IND (JP) 1999-07-21 CN disclosed