Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221667 | 0.83 | HRH3 (0.35) | HRH3KDM4EGLAL3MBTL1 | |
| SCHEMBL8681484 | 0.83 | TGFBR1 (0.37) | HRH3KDM4EGLAL3MBTL1 | |
| SCHEMBL19512283 | 0.80 | HRH3 (0.35) | HRH3KDM4EGLAL3MBTL1 | |
| SCHEMBL202411 | 0.79 | TGFBR1 (0.41) | HRH3KDM4E | |
| SCHEMBL15254146 | 0.78 | HRH3 (0.34) | HRH3KDM4EGLAL3MBTL1 | |
| SCHEMBL2747744 | 0.77 | HRH3 (0.33) | HRH3KDM4E | |
| SCHEMBL8684475 | 0.75 | HRH3 (0.50) | HRH3KDM4EGLAL3MBTL1 | |
| SCHEMBL4918832 | 0.75 | HRH3 (0.33) | HRH3KDM4EGLAL3MBTL1 | |
| SCHEMBL13455886 | 0.75 | HRH3 (0.33) | HRH3KDM4EGLAL3MBTL1 | |
| SCHEMBL9816463 | 0.75 | KDM4E (0.45) | HRH3KDM4EGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139456-B2 | Chelating compounds and immobilized tethered chelators | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-09-22 | — | — | US | disclosed |
| US-20120061325-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2012-03-15 | — | — | US | disclosed |
| US-8066883-B2 | Removing aluminum from solution using chelating compounds and immobilized tethered chelators | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2011-11-29 | — | — | US | disclosed |
| US-20110168636-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-07-14 | — | — | US | disclosed |
| US-7932326-B2 | Chelating compounds and immobilized tethered chelators | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2011-04-26 | — | — | US | disclosed |
| US-20090261043-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2009-10-22 | — | — | US | disclosed |
| US-20050027120-A1 | Method for the synthesis of amides and related products from esters or ester-like compounds | REACTIMEX, S.A. DE C.V. (MX) | 2005-02-03 | — | — | US | disclosed |
| US-4978786-A | Chemical process for the preparation of oxamide derivatives and compounds prepared thereby | ENICHEM ANIC S.P.A. (IT) | 1990-12-18 | — | — | US | disclosed |
| EP-0245631-B1 | CHEMICAL PROCESS FOR THE PREPARATION OF OXAMIDE DERIVATIVES. | ENICHEM ANIC S.p.A. (IT) | 1990-08-01 | — | — | EP | disclosed |
| EP-0245631-A2 | Chemical process for the preparation of oxamide derivatives. | ENICHEM ANIC S.p.A. (IT) | 1987-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120061325-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | BTD, TTPA, SLC39A7 | HRH3 1884/4885KDM4E 472/4885GLA 515/4885 |
| US-20090261043-A1 | CHELATING COMPOUNDS AND IMMOBILIZED TETHERED CHELATORS | BTD, SLC30A7, SLC39A7 | HRH3 2220/4885KDM4E 576/4885GLA 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.