SCHEMBL221667

SCHEMBL221667

C[C](C)C(=O)NC(CO)(CO)CO

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.35
KDM4E B2RXH2 2/20 0.33
PKM P14618 1/20 0.33
GLA P06280 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL452629 0.83 HRH3 (0.35) HRH3KDM4EGLAL3MBTL1
SCHEMBL202411 0.80 TGFBR1 (0.41) HRH3KDM4EPKM
SCHEMBL25763081 0.79 HRH3 (0.35) HRH3KDM4EPKM
SCHEMBL2747744 0.78 HRH3 (0.33) HRH3KDM4EPKM
SCHEMBL9816463 0.78 KDM4E (0.45) HRH3KDM4EPKMGLAL3MBTL1
SCHEMBL275365 0.75 TGFBR1 (0.37) HRH3KDM4EPKM
SCHEMBL8681484 0.74 TGFBR1 (0.37) HRH3KDM4EGLAL3MBTL1
SCHEMBL12328360 0.73 KDM4E (0.32) HRH3KDM4EPKM
SCHEMBL1724193 0.73 TGFBR1 (0.36) HRH3
SCHEMBL18622068 0.72 PKM (0.45) HRH3KDM4EPKML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9340498-B2 Raft polymerisation COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESERACH ORGANISATION (AU) 2016-05-17 US claimed
WO-2023102600-A1 SYNTHESIS OF AMPHIPHILIC BLOCK COPOLYMERS AND POLYMERIC NANOFIBERS PRODUCED THEREFROM NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2023-06-15 WO disclosed
EP-2389395-B1 RAFT POLYMERISATION COMMW SCIENT IND RES ORG (AU) 2017-03-29 EP disclosed
US-9340498-B2 Raft polymerisation COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESERACH ORGANISATION (AU) 2016-05-17 US disclosed
US-20120004381-A1 RAFT POLYMERISATION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2012-01-05 US disclosed
EP-2389395-A1 RAFT POLYMERISATION Commonwealth Scientific and Industrial Research Organisation (AU) 2011-11-30 EP disclosed
US-20110256644-A1 MASKS FOR MICROLITHOGRAPHY AND METHODS OF MAKING AND USING SUCH MASKS MICRON TECHNOLOGY, INC. (US) 2011-10-20 US disclosed
WO-2010083569-A1 RAFT POLYMERISATION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-07-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004381-A1 RAFT POLYMERISATION OXGR1, FRG1, MSR1 HRH3 909/4885KDM4E 4333/4885PKM 4237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.