Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.58 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | QDPR | P09417 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.43 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | TTK | P33981 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954009 | 0.87 | CYP3A4 (0.94) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| Orthotolidine SCHEMBL49414 | 0.84 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| Orthotolidine SCHEMBL29386552 | 0.84 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| Orthotolidine SCHEMBL29365329 | 0.84 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL3342706 | 0.83 | NTRK1 (0.55) | CYP3A4ALDH1A1TSHRTDP1AAK1 | |
| Orthotolidine SCHEMBL11189493 | 0.82 | CYP3A4 (0.94) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| Orthotolidine SCHEMBL22129692 | 0.82 | CYP3A4 (0.94) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| Orthotolidine SCHEMBL20547383 | 0.82 | CYP3A4 (0.94) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| Orthotolidine SCHEMBL2812115 | 0.82 | CYP3A4 (0.94) | CYP3A4ALDH1A1TSHRTDP1MAPT | |
| Orthotolidine SCHEMBL38664709 | 0.82 | CYP3A4 (0.94) | CYP3A4ALDH1A1TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230225188-A1 | ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-07-13 | — | — | US | disclosed |
| US-20230225188-A1 | ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-07-13 | — | — | US | disclosed |
| US-8211919-B2 | Amide derivatives as rock inhibitors | ASTELLAS PHARMA INC. (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20090105231-A1 | AMIDE DERIVATIVES AS ROCK INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1922306-A2 | AMIDE DERIVATIVES AS ROCK INHIBITORS | Astellas Pharma Inc. (JP) | 2008-05-21 | — | — | EP | disclosed |
| CN-100355751-C | 2-substd. 4-heteroaryl-pyrimidines and their use in treatment of proliferative disorders | CYCLACEL LTD (GB) | 2007-12-19 | — | — | CN | disclosed |
| WO-2007026920-A2 | AMIDE DERIVATIVES AS ROCK INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2007-03-08 | — | — | WO | disclosed |
| US-4506075-A | PYRIDINE, BENZOYL CHLORIDE, 3-METHYL-N,N-DIALKYLBENZENEAMINE, COPPER | STERLING DRUG INC. (US) | 1985-03-19 | — | — | US | disclosed |
| US-4415578-A | INOTROPIC AGENTS | STERLING DRUG INC. (US) | 1983-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225188-A1 | ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE | GPX1, CRY1, LAGE3 | CYP3A4 330/4885ALDH1A1 11/4885TSHR 3910/4885 |
| US-20090105231-A1 | AMIDE DERIVATIVES AS ROCK INHIBITORS | ROCK1, ROCK2, RHOA | CYP3A4 4098/4885ALDH1A1 3985/4885TSHR 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.