Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20248 | 1.00 | NPSR1 (0.44) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL19246 | 1.00 | NPSR1 (0.44) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL19706368 | 0.88 | NPSR1 (0.43) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL17164559 | 0.86 | NPSR1 (0.44) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL17164558 | 0.86 | NPSR1 (0.44) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL17164585 | 0.86 | — | — | |
| SCHEMBL18936288 | 0.86 | — | — | |
| SCHEMBL17164546 | 0.85 | HTT (0.37) | NPSR1GLO1 | |
| SCHEMBL17164571 | 0.85 | ATM (0.40) | NPSR1GLO1ALDH1A1MAPTTDP1 | |
| SCHEMBL17164569 | 0.85 | ATM (0.40) | NPSR1GLO1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4737450-A1 | HETEROAROMATIC FORMAMIDE COMPOUNDS AND USES THEREOF IN MEDICINE | Longwood Pharmaceuticals (Hangzhou) Co., Ltd (CN) | 2026-05-06 | — | — | EP | disclosed |
| US-20250320201-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS INC (US) | 2025-10-16 | — | — | US | disclosed |
| EP-4619388-A1 | CATHEPSIN L INHIBITORS | Biofront Therapeutics (Beijing) Co., Ltd. (CN) | 2025-09-24 | — | — | EP | disclosed |
| US-20250262201-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. | 2025-08-21 | — | — | US | disclosed |
| US-20250171438-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. | 2025-05-29 | — | — | US | disclosed |
| US-20250171437-A1 | (4-BENZO[D]OXAZOL-2-YL)-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-5(4H)-YL)METHANONE DERIVATIVES AS MUTANT PAH STABILIZERS FOR THE TREATMENT OF PHENYLKETONURIA | AGIOS PHARMACEUTICALS, INC. | 2025-05-29 | — | — | US | disclosed |
| CN-119604497-A | Heteroaromatic carboxamides and their use in medicine | 远森制药（杭州）有限公司 | 2025-03-11 | — | — | CN | disclosed |
| US-20250059196-A1 | TRICYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2025-02-20 | — | — | US | disclosed |
| WO-2025001956-A1 | HETEROAROMATIC FORMAMIDE COMPOUNDS AND USES THEREOF IN MEDICINE | 远森制药（杭州）有限公司 | 2025-01-02 | — | — | WO | disclosed |
| EP-4458819-A1 | TRICYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-11-06 | — | — | EP | disclosed |
| EP-2150536-A1 | PROCESS FOR THE PRODUCTION OF PYRAZOLES | Syngeta Participations AG (CH) | 2010-02-10 | — | — | EP | disclosed |
| US-7585998-B2 | Method for producing difluoro-acetyl-acetic acid alkylesters | BAYER CROPSCIENCE AG (DE) | 2009-09-08 | — | — | US | disclosed |
| EP-2008996-A1 | Process for the production of pyrazoles | Syngeta Participations AG (CH) | 2008-12-31 | — | — | EP | disclosed |
| WO-2009000442-A2 | PROCESSES FOR THE PREPARATION OF PYRAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008145257-A1 | PROCESS FOR THE PRODUCTION OF PYRAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-12-04 | — | — | WO | disclosed |
| EP-1997808-A1 | Process for the production of pyrazoles | Syngeta Participations AG (CH) | 2008-12-03 | — | — | EP | disclosed |
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | SAGAMI CHEMICAL RESEARCKH CENTER (JP) | 2008-06-26 | — | — | US | disclosed |
| US-20080108686-A1 | N-(Ortho-Phenyl)-1-Methyl-3-Difluoromethylpyrazole-4-Carboxanilides And Their Use As Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080108686-A1 | N-(Ortho-Phenyl)-1-Methyl-3-Difluoromethylpyrazole-4-Carboxanilides And Their Use As Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20060149091-A1 | Method for producing difluoro-acetyl-acetic acid alkylesters | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250262201-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | PAH, KDM8, PHF8 | NPSR1 2136/4885GLO1 216/4885ALDH1A1 865/4885 |
| US-20250171437-A1 | (4-BENZO[D]OXAZOL-2-YL)-6,7-DIHYDRO-1H-IMIDAZO[4,5-C]PYRIDINE-5(4H)-YL)METHANONE DERIVATIVES AS MUTANT PAH STABILIZERS FOR THE TREATMENT OF PHENYLKETONURIA | PAH, BCKDK, PKM | NPSR1 4020/4885GLO1 711/4885ALDH1A1 634/4885 |
| US-20250059196-A1 | TRICYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | WEE1, CYP51A1, WEE2 | NPSR1 4156/4885GLO1 890/4885ALDH1A1 792/4885 |
| US-20250320201-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | PAH, KDM8, PHF8 | NPSR1 2136/4885GLO1 216/4885ALDH1A1 865/4885 |
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | CYP4Z1, CYP3A4, HACL2 | NPSR1 4153/4885GLO1 657/4885ALDH1A1 69/4885 |
| US-20080108686-A1 | N-(Ortho-Phenyl)-1-Methyl-3-Difluoromethylpyrazole-4-Carboxanilides And Their Use As Fungicides | CBR3, DDT, CBR1 | NPSR1 1221/4885GLO1 818/4885ALDH1A1 1090/4885 |
| US-20060149091-A1 | Method for producing difluoro-acetyl-acetic acid alkylesters | APEH, ACACA, NAT1 | NPSR1 2679/4885GLO1 1239/4885ALDH1A1 51/4885 |
| US-20250171438-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | PAH, KDM8, PHF8 | NPSR1 2136/4885GLO1 216/4885ALDH1A1 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.