SCHEMBL4529434

SCHEMBL4529434

CCc1cccc(-c2cccc(CC)c2CC)c1CC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.50
GABRB2 P47870 4/20 0.50
TAAR1 Q96RJ0 2/20 0.41
HTR1A P08908 1/20 0.41
CYP2D6 P10635 1/20 0.39
KCNH2 Q12809 1/20 0.38
SCN5A Q14524 1/20 0.38
PDK2 Q15119 2/20 0.38
ANPEP P15144 1/20 0.38
DPP4 P27487 1/20 0.38
MGLL Q99685 1/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
LMNA P02545 1/20 0.35
CSNK2A2 P19784 1/20 0.35
CSNK2B P67870 1/20 0.35
CSNK2A1 P68400 1/20 0.35
CSNK2A3 Q8NEV1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL473257 0.93 GABRA1 (0.44) GABRA1GABRB2TAAR1HTR1ACYP2D6
SCHEMBL245773 0.86 GABRA1 (0.57) GABRA1GABRB2TAAR1HTR1AKCNH2
SCHEMBL983104 0.85 GABRA1 (0.48) GABRA1GABRB2HTR1APDK2ANPEP
SCHEMBL1647071 0.85 ALDH1A1 (0.50) GABRA1GABRB2TAAR1HTR1ACYP2D6
SCHEMBL473270 0.84 PDCD1 (0.50) GABRA1GABRB2CYP2D6DPP4
SCHEMBL5587368 0.84 GABRA1 (0.52) GABRA1GABRB2ANPEPDPP4LMNA
SCHEMBL11198848 0.84 TP53 (0.41) GABRA1GABRB2TAAR1HTR1A
Methane SCHEMBL28776675 0.83 GABRA1 (0.55) GABRA1GABRB2TAAR1HTR1AKCNH2
SCHEMBL31498538 0.83 GABRA1 (0.55) GABRA1GABRB2TAAR1HTR1AKCNH2
Ammonia Solution, Strong SCHEMBL27320869 0.83 GABRA1 (0.55) GABRA1GABRB2TAAR1HTR1AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118724765-A Method for preparing sulfonamide derivative by using low-cost metal catalysis 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2024-10-01 CN claimed
EP-3274318-B1 PRODUCTION OF BIPHENYL COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-02-26 EP claimed
EP-3274318-A1 PRODUCTION OF BIPHENYL COMPOUNDS ExxonMobil Chemical Patents Inc. (US) 2018-01-31 EP claimed
US-9708230-B2 Production of biphenyl compounds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-07-18 US claimed
US-20160280616-A1 Production of Biphenyl Compounds EXXONMOBIL CHEMICAL PATENTS INC. 2016-09-29 US claimed
WO-2016153575-A1 PRODUCTION OF BIPHENYL COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-09-29 WO claimed
EP-0347500-B1 METHOD OF MAKING ETHYLBIPHENYLS NIPPON STEEL CHEMICAL CO., LTD. (JP) 1993-08-25 EP claimed
US-4943553-A ETHYLATION TRANSETHYLATION NIPPON STEEL CHEMICAL CO., LTD. (JP) 1990-07-24 US claimed
EP-0347500-A1 Method of making ethylbiphenyls NIPPON STEEL CHEMICAL CO., LTD. (JP) 1989-12-27 EP claimed
US-12516147-B2 Aldimines and uses thereof BOSTIK SA (FR) 2026-01-06 US disclosed
EP-4617336-A1 TWO-COMPONENT COMPOSITION Bostik SA (FR) 2025-09-17 EP disclosed
EP-4077273-B1 ALDIMINES AND USES THEREOF BOSTIK SA (FR) 2025-04-02 EP disclosed
US-20250034440-A1 (METH)ACRYLATE-BASED TWO-COMPONENT ADHESIVE FORMULATION FOR ASSEMBLING WIND TURBINE BLADES BOSTIK SA (FR) 2025-01-30 US disclosed
US-12152175-B2 Composition made from (meth)acrylate monomers BOSTIK SA (FR) 2024-11-26 US disclosed
US-4943553-A ETHYLATION TRANSETHYLATION NIPPON STEEL CHEMICAL CO., LTD. (JP) 1990-07-24 US disclosed
EP-0347500-A1 Method of making ethylbiphenyls NIPPON STEEL CHEMICAL CO., LTD. (JP) 1989-12-27 EP disclosed
US-4599445-A Process for benzophenone tetracarboxylic acid THE DOW CHEMICAL COMPANY (US) 1986-07-08 US disclosed
US-4562271-A Preparation of 3-alkanoyloxyphthalides THE UPJOHN COMPANY (US) 1985-12-31 US disclosed
US-4485247-A 3-Alkanoyloxyphthalides THE UPJOHN COMPANY (US) 1984-11-27 US disclosed
EP-0125342-A1 Process for preparation of aromatic polycarboxylic acids and intermediates therefor THE UPJOHN COMPANY (US) 1984-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160280616-A1 Production of Biphenyl Compounds AHR, ARNT, CYP1B1 GABRA1 1164/4885GABRB2 625/4885TAAR1 1797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.