SCHEMBL5587368

SCHEMBL5587368

CCc1cccc(-c2cccc(O)c2O)c1CC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.52
GABRB2 P47870 4/20 0.52
IAPP P10997 5/20 0.45
ANPEP P15144 1/20 0.44
DPP4 P27487 1/20 0.44
ADAMTS4 O75173 1/20 0.39
ALDH1A1 P00352 1/20 0.39
EGFR P00533 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
LMNA P02545 1/20 0.39
FYN P06241 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
MMP8 P22894 1/20 0.39
CA6 P23280 1/20 0.39
CDK2 P24941 1/20 0.39
MMP12 P39900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL983104 0.87 GABRA1 (0.48) GABRA1GABRB2IAPPANPEPDPP4
SCHEMBL5587931 0.85 GABRA1 (0.56) GABRA1GABRB2IAPPANPEPDPP4
SCHEMBL4529434 0.84 GABRA1 (0.50) GABRA1GABRB2ANPEPDPP4LMNA
Calcium SCHEMBL31214809 0.82 GABRA1 (0.56) GABRA1GABRB2IAPPANPEPDPP4
Calcium SCHEMBL31255832 0.80 GABRA1 (0.54) GABRA1GABRB2IAPPANPEPDPP4
SCHEMBL707284 0.80 GABRA1 (0.58) GABRA1GABRB2IAPPANPEPDPP4
SCHEMBL30116230 0.80 GABRA1 (0.58) GABRA1GABRB2IAPPANPEPDPP4
SCHEMBL15668660 0.80 HNF4A (0.45) ALDH1A1CA1CA2MMP2HPGD
SCHEMBL10679098 0.79 GABRA1 (0.48) GABRA1GABRB2IAPPANPEPDPP4
SCHEMBL2870900 0.79 ANPEP (0.49) GABRA1GABRB2ANPEPDPP4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 GABRA1 3688/4885GABRB2 3686/4885IAPP 4111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.