Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 4/20 | 0.47 |
| ▸ | HEXA | P06865 | 2/20 | 0.47 |
| ▸ | HEXB | P07686 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500167 | 0.84 | DHFR (0.61) | DHFRHEXAHEXBSMN1; SMN2KDM4E | |
| SCHEMBL9289229 | 0.76 | ALDH1A1 (0.55) | DHFRHEXAHEXBSMN1; SMN2KDM4E | |
| SCHEMBL12368258 | 0.75 | HEXA (0.47) | DHFRHEXAHEXBSMN1; SMN2KDM4E | |
| SCHEMBL1885367 | 0.74 | HEXA (0.50) | DHFRHEXAHEXBSMN1; SMN2ALDH1A1 | |
| SCHEMBL12368257 | 0.74 | HEXA (0.64) | DHFRHEXAHEXBSMN1; SMN2ALDH1A1 | |
| SCHEMBL27459436 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4ENPC1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL1889973 | 0.73 | HEXA (0.49) | DHFRHEXAHEXBSMN1; SMN2ALDH1A1 | |
| Biphenyl-4-Amine SCHEMBL7061324 | 0.72 | CYP3A4 (0.62) | SMN1; SMN2KDM4ENPC1ALDH1A1TP53 | |
| Biphenyl SCHEMBL27806523 | 0.72 | CES1 (0.50) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7162150 | 0.72 | DHFR (0.66) | DHFRHEXAHEXBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018150-A1 | 5-Ht2b Receptor Antagonists | ASTERAND UK LIMITED (GB) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018150-A1 | 5-Ht2b Receptor Antagonists | HTR2B, HTR1B, HTR3B | DHFR 1058/4885HEXA 748/4885HEXB 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.