Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 11/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4507782 | 0.94 | SOAT1 (0.65) | SOAT1NPSR1ALDH1A1POLBRAB9A | |
| SCHEMBL4526190 | 0.88 | SOAT1 (0.68) | SOAT1POLB | |
| SCHEMBL4513155 | 0.86 | SOAT1 (0.50) | SOAT1CYP1A2CYP3A4GAACYP2D6 | |
| SCHEMBL6282739 | 0.83 | SOAT1 (0.73) | SOAT1ALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL4518624 | 0.83 | SOAT1 (0.68) | SOAT1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL4530232 | 0.82 | SOAT1 (0.68) | SOAT1CYP1A2GAACYP2D6CYP2C19 | |
| SCHEMBL4526617 | 0.82 | SOAT1 (0.67) | SOAT1NPSR1ALDH1A1POLBRAB9A | |
| SCHEMBL4513200 | 0.80 | SOAT1 (1.00) | SOAT1ALDH1A1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL4529809 | 0.80 | SOAT1 (0.49) | SOAT1NPSR1ALDH1A1RAB9A | |
| SCHEMBL4513121 | 0.80 | SOAT1 (0.68) | SOAT1ALDH1A1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560547-B2 | Hydroxyalkyl cyclic diamine compounds | KOWA CO., LTD. (JP) | 2009-07-14 | — | — | US | disclosed |
| US-20070088159-A1 | HYDROXYALKYL CYCLIC DIAMINE COMPOUNDS | KOWA CO., LTD. (JP) | 2007-04-19 | — | — | US | disclosed |
| US-7176306-B2 | Hydroxyalkyl cyclic diamine compound | KOWA CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| EP-1571144-A1 | HYDROXYALKYLATED CYCLIC DIAMINE COMPOUND | Kowa Co., Ltd. (JP) | 2005-09-07 | — | — | EP | disclosed |
| US-20040176593-A1 | Hydroxyalkyl cyclic diamine compound | KOWA CO., LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176593-A1 | Hydroxyalkyl cyclic diamine compound | DDC, AOC1, ODC1 | SOAT1 1314/4885CYP1A2 966/4885CYP3A4 1100/4885 |
| US-20070088159-A1 | HYDROXYALKYL CYCLIC DIAMINE COMPOUNDS | HDHD5, DDC, DDT | SOAT1 1023/4885CYP1A2 1679/4885CYP3A4 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.