Cyclohexylamine

Cyclohexylamine

SCHEMBL4530522

CCC[Si](O)(O)O.NC1CCCCC1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 2/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.36
ALDH1A1 P00352 2/20 0.34
EPHX1 P07099 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
NAAA Q02083 2/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
ENPP2 Q13822 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL2067439 0.78 CYP1A2 (0.42) MMP8MMP1MMP2ALDH1A1CYP1A2
Cyclooctanamine SCHEMBL11463223 0.76 ALDH1A1 (0.41) MMP8MMP1MMP2ALDH1A1EPHX1
Alcohol SCHEMBL11461188 0.76 ALDH1A1 (0.41) MMP8MMP1MMP2ALDH1A1EPHX1
Cyclohexylamine SCHEMBL7322768 0.76 ALDH1A1 (0.41) MMP8MMP1MMP2ALDH1A1EPHX1
Cycloheptanamine SCHEMBL11457856 0.76 ALDH1A1 (0.41) MMP8MMP1MMP2ALDH1A1EPHX1
Cyclohexylamine SCHEMBL4447887 0.75 SHBG (0.39) MMP8MMP1MMP2ALDH1A1CYP1A2
Cyclohexylamine SCHEMBL304798 0.75 MMP8 (0.33) MMP8MMP1MMP2ALDH1A1CYP1A2
Cyclohexylamine SCHEMBL588721 0.74 CYP1A2 (0.50) EPHX1CYP1A2NAAAENPP2
Cyclohexylamine SCHEMBL1782618 0.74 CYP1A2 (0.39) MMP8MMP1MMP2ALDH1A1EPHX1
Cyclohexylamine SCHEMBL29057250 0.74 CYP1A2 (0.50) ALDH1A1CYP1A2NAAAENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed