Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.59 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976311 | 0.85 | PTGS2 (0.61) | NTRK1PLK3CA1CA2LMNA | |
| SCHEMBL29349443 | 0.84 | KMT2A (0.69) | NTRK1PLK3KMT2AMEN1KDM4E | |
| SCHEMBL693914 | 0.84 | KMT2A (0.69) | NTRK1PLK3KMT2AMEN1KDM4E | |
| SCHEMBL28162855 | 0.82 | KMT2A (0.67) | NTRK1PLK3KMT2AMEN1KDM4E | |
| SCHEMBL28847414 | 0.82 | KMT2A (0.67) | NTRK1PLK3KMT2AMEN1KDM4E | |
| SCHEMBL31717956 | 0.82 | KMT2A (0.67) | NTRK1PLK3KMT2AMEN1KDM4E | |
| SCHEMBL7703075 | 0.82 | PLA2G2A (0.73) | NTRK1PLK3KMT2AMEN1KDM4E | |
| SCHEMBL2331449 | 0.82 | ADORA3 (0.63) | NTRK1PLK3KMT2AMEN1KDM4E | |
| SCHEMBL25012774 | 0.81 | PTGS2 (0.44) | KMT2AMEN1KDM4ECYP3A4CA1 | |
| SCHEMBL17751079 | 0.81 | PTGS2 (0.44) | KMT2AMEN1KDM4ECYP3A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994023715-A1 | USE OF FLAVONOIDS TO TREAT MULTIDRUG RESISTANT CANCER CELLS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-10-27 | — | — | WO | claimed |
| US-20230190720-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS | KAHRS, Bjoern Colin (CH) | 2023-06-22 | — | — | US | disclosed |
| US-11628132-B2 | Minoxidil adjuvant therapies | Jupiter Wellness, Inc. (US) | 2023-04-18 | — | — | US | disclosed |
| CN-115850292-A | Novel C-4 substituted coumarin compounds and preparation method and application thereof | 昆明医科大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-114751912-B | Application of isopentenyl substituted bisphenylpyridone compound | 昆明医科大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-114751912-A | New application of isopentenyl substituted bisphenylpyridone compound | 昆明医科大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-113785937-A | Preparation method of glutinous rice flour with low glycemic index and product thereof | 江苏科技大学 | 2021-12-14 | — | — | CN | disclosed |
| CN-113785937-A | Preparation method of glutinous rice flour with low glycemic index and product thereof | 江苏科技大学 | 2021-12-14 | — | — | CN | disclosed |
| CN-112409368-B | C-4 substituted coumarin compounds and preparation method and application thereof | 昆明医科大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-112409368-A | C-4 substituted coumarin compounds and preparation method and application thereof | 昆明医科大学 | 2021-02-26 | — | — | CN | disclosed |
| WO-2012062925-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | AKRON MOLECULES GMBH (AT) | 2012-05-18 | — | — | WO | disclosed |
| WO-2005049002-A1 | MATERIALS AND METHODS FOR IMPROVING ALCOHOL METABOLISM AND ALLEVIATING THE EFFECTS OF HANGOVERS | OMEGA BIO-PHARMA INTERNATIONAL LTD. (US) | 2005-06-02 | — | — | WO | disclosed |
| EP-1024958-A1 | MANUFACTURE OF LITHOGRAPHIC PRINTING FORMS | HORSELL GRAPHIC INDUSTRIES LIMITED (GB) | 2000-08-09 | — | — | EP | disclosed |
| EP-1024963-A1 | PATTERN FORMATION | Kodak Polychrome Graphics Company Ltd. (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999021725-A1 | PATTERN FORMATION | KODAK POLYCHROME GRAPHICS COMPANY LTD (US) | 1999-05-06 | — | — | WO | disclosed |
| WO-1999021715-A1 | MANUFACTURE OF LITHOGRAPHIC PRINTING FORMS | KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) | 1999-05-06 | — | — | WO | disclosed |
| EP-0680517-A1 | METHODS AND DIAGNOSTIC KITS UTILIZING MAMMALIAN STRESS PROMOTERS TO DETERMINE TOXICITY OF A COMPOUND | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994023715-A1 | USE OF FLAVONOIDS TO TREAT MULTIDRUG RESISTANT CANCER CELLS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-10-27 | — | — | WO | disclosed |
| US-5336685-A | Use of flavonoids to treat multidrug resistant cancer cells | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-08-09 | — | — | US | disclosed |
| WO-1994017208-A1 | METHODS AND DIAGNOSTIC KITS UTILIZING MAMMALIAN STRESS PROMOTERS TO DETERMINE TOXICITY OF A COMPOUND | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1994-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190720-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS | PPARG, PPARA, PPARD | NTRK1 3637/4885PLK3 1119/4885KMT2A 912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.