Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4361277 | 0.95 | MAPK14 (0.40) | LMNACD274SLC6A2SLC6A4NAMPT | |
| SCHEMBL4530802 | 0.91 | LMNA (0.51) | LMNACD274HPGDSLC6A2SLC6A4 | |
| SCHEMBL4540129 | 0.90 | ALDH1A1 (0.43) | LMNACD274HPGDNAMPTCHRM4 | |
| SCHEMBL4538002 | 0.90 | NPY2R (0.42) | CD274SLC6A4NAMPTGAA | |
| SCHEMBL4350134 | 0.89 | CD274 (0.36) | LMNACD274HPGDSLC6A2SLC6A4 | |
| SCHEMBL4358687 | 0.89 | SMN1; SMN2 (0.46) | LMNA | |
| SCHEMBL4533472 | 0.88 | KMT2A (0.44) | SLC6A4GAA | |
| SCHEMBL4538200 | 0.87 | POLB (0.42) | LMNACD274HPGDGAA | |
| SCHEMBL4360517 | 0.87 | NAMPT (0.41) | LMNACD274NAMPT | |
| SCHEMBL4533099 | 0.87 | GPR119 (0.47) | CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |