Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353588 | 0.88 | PIK3CA (0.43) | PIK3CAGPR119CYP3A4SLC9A1NAMPT | |
| SCHEMBL4349922 | 0.85 | PTPN2 (0.43) | PIK3CACYP3A4SLC9A1 | |
| SCHEMBL4537918 | 0.85 | PTPN2 (0.43) | PIK3CACYP3A4SLC9A1 | |
| SCHEMBL4356473 | 0.85 | PTPN2 (0.43) | PIK3CACYP3A4SLC9A1 | |
| SCHEMBL4347963 | 0.85 | NPC1 (0.46) | PIK3CAHPGDPTGS2 | |
| SCHEMBL4535480 | 0.84 | LMNA (0.42) | PIK3CAGPR119CYP3A4NAMPTUSP30 | |
| SCHEMBL4356151 | 0.83 | GAA (0.42) | PIK3CAGPR119SLC9A1 | |
| SCHEMBL4347838 | 0.83 | NAMPT (0.44) | PIK3CAGPR119CYP3A4SLC9A1NAMPT | |
| SCHEMBL4347925 | 0.82 | USP30 (0.40) | PIK3CAGPR119PTGS2USP30 | |
| SCHEMBL13586033 | 0.82 | LMNA (0.45) | PIK3CASLC9A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |