Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356151 | 0.89 | GAA (0.42) | PIK3CAGPR119SMN1; SMN2CYP2C19CYP2C9 | |
| SCHEMBL4353588 | 0.87 | PIK3CA (0.43) | LMNAPIK3CAGPR119CYP3A4CYP2C9 | |
| SCHEMBL4531447 | 0.84 | PIK3CA (0.44) | PIK3CAGPR119CYP3A4USP30NAMPT | |
| SCHEMBL4347925 | 0.83 | USP30 (0.40) | PIK3CAGPR119USP30 | |
| SCHEMBL4355702 | 0.83 | PIK3CA (0.37) | PIK3CAGPR119USP30CYP11B2 | |
| SCHEMBL4353423 | 0.83 | PIK3CA (0.38) | PIK3CAGPR119USP30 | |
| SCHEMBL4537918 | 0.83 | PTPN2 (0.43) | LMNAPIK3CASMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL4349922 | 0.83 | PTPN2 (0.43) | LMNAPIK3CASMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL4356473 | 0.83 | PTPN2 (0.43) | LMNAPIK3CASMN1; SMN2CYP2C19CYP3A4 | |
| SCHEMBL4348569 | 0.82 | GPR119 (0.39) | PIK3CAGPR119USP30CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |