Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RGS4 | P49798 | 1/20 | 0.32 |
| ▸ | RGS8 | P57771 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4532617 | 0.83 | ALDH1A1 (0.40) | ALDH1A1THRBPOLBMAPTL3MBTL1 | |
| SCHEMBL10587862 | 0.81 | ALDH1A1 (0.38) | ALDH1A1THRBPOLBMAPTL3MBTL1 | |
| SCHEMBL4518207 | 0.80 | TSHR (0.38) | ALDH1A1THRBPOLBMAPTL3MBTL1 | |
| SCHEMBL19036772 | 0.79 | ALDH1A1 (0.36) | ALDH1A1THRBPOLBMAPTKDM4E | |
| SCHEMBL20161758 | 0.72 | ALDH1A1 (0.38) | ALDH1A1THRBPOLBMAPTL3MBTL1 | |
| SCHEMBL19036626 | 0.72 | GAA (0.37) | ALDH1A1THRBL3MBTL1 | |
| SCHEMBL20161623 | 0.70 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTKDM4E | |
| SCHEMBL12293892 | 0.66 | — | — | |
| SCHEMBL8443038 | 0.64 | POLB (0.39) | ALDH1A1THRBPOLBMAPTL3MBTL1 | |
| SCHEMBL20561158 | 0.64 | ALDH1A1 (0.62) | ALDH1A1POLBMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108614-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | HYDRA BIOSCIENCES, INC. | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108614-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES | ELANE, CASP3, MMP8 | ALDH1A1 1104/4885THRB 4543/4885POLB 2332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.