SCHEMBL4532875

SCHEMBL4532875

CCOC(=O)c1cn(O)nn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
LMNA P02545 1/20 0.56
HPGD P15428 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
GLA P06280 1/20 0.50
MAPK1 P28482 2/20 0.49
CYP1A2 P05177 1/20 0.49
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 1/20 0.46
TSHR P16473 1/20 0.46
KMT2A Q03164 1/20 0.46
POLB P06746 2/20 0.44
SPR P35270 1/20 0.44
TP53 P04637 1/20 0.44
GAA P10253 1/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
CA12 O43570 1/20 0.43
CA4 P22748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2515677 0.82 ALDH1A1 (0.60) ALDH1A1LMNAHPGDSMN1; SMN2GLA
SCHEMBL16093587 0.81 ALDH1A1 (0.67) ALDH1A1LMNAHPGDSMN1; SMN2GLA
SCHEMBL14405394 0.81 ALDH1A1 (0.55) ALDH1A1LMNAHPGDSMN1; SMN2GLA
SCHEMBL3589726 0.81 ALDH1A1 (0.55) ALDH1A1LMNAHPGDSMN1; SMN2GLA
SCHEMBL3677898 0.80 ALDH1A1 (0.62) ALDH1A1LMNAHPGDSMN1; SMN2GLA
SCHEMBL23382244 0.79 ALDH1A1 (0.60) ALDH1A1LMNAHPGDSMN1; SMN2GLA
SCHEMBL12223728 0.78 ALDH1A1 (0.63) ALDH1A1LMNAHPGDSMN1; SMN2GLA
SCHEMBL1412523 0.78 ALDH1A1 (0.52) ALDH1A1LMNAHPGDSMN1; SMN2GLA
SCHEMBL25984988 0.78 ALDH1A1 (0.52) ALDH1A1LMNAHPGDSMN1; SMN2GLA
SCHEMBL20995354 0.77 ALDH1A1 (0.51) ALDH1A1LMNAHPGDSMN1; SMN2GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001909-A1 Method for Preparing a Peptide With CCK Receptor Modulatory Activity CRMH HONG KONG INST OF SCIENCE & INNOVATION CHINESE ACADEMY OF SCIENCES (CN) 2026-01-01 US claimed
EP-4662222-A1 PROCESS FOR THE PREPARATION OF TETRAPEPTIDE FRAGMENT OF LIRAGLUTIDE Fresenius Kabi Oncology Ltd (IN) 2025-12-17 EP claimed
US-20250188118-A1 LIQUID PHASE PEPTIDE SYNTHESIS METHODS AMGEN INC. (US) 2025-06-12 US claimed
WO-2025122535-A2 LIQUID PHASE PEPTIDE SYNTHESIS METHODS AMGEN INC. (US) 2025-06-12 WO claimed
EP-4565705-A2 COMPOSITIONS AND METHODS FOR MODIFYING MULLER GLIAL CELLS The Johns Hopkins University (US) 2025-06-11 EP claimed
CN-119904695-A Construction method of macular degeneration classification system and macular degeneration classification system 北京石油化工学院 2025-04-29 CN claimed
CN-118530294-B Aryl diamine immobilized linker, precursor thereof, preparation method and application 浙江大学 2025-02-14 CN claimed
CN-119264965-A Alkylated nanoparticle, preparation method and application thereof 湖南大学 2025-01-07 CN claimed
CN-118956754-A Induced pluripotent stem cell directional differentiation kit and method 上海昂朴生物科技有限公司 2024-11-15 CN claimed
CN-118852340-A Preparation method of polypeptide with CCK receptor agonism/antagonism activity 中国科学院香港创新研究院再生医学与健康创新中心 2024-10-29 CN claimed
CN-115044274-B Ceramic particle modified fiber epoxy composite coating and preparation method and application thereof 宁波科鑫腐蚀控制工程有限公司 2023-04-28 CN claimed
WO-2022206871-A1 PREPARATION AND PURIFICATION METHOD FOR ANTIBODY DRUG CONJUGATE INTERMEDIATE REMEGEN CO., LTD. (CN) 2022-10-06 WO claimed
CN-115044274-A Ceramic particle modified fiber epoxy composite coating and preparation method and application thereof 宁波科鑫腐蚀控制工程有限公司 2022-09-13 CN claimed
US-20210253634-A1 PROCESS FOR THE LIQUID PHASE SYNTHESIS OF H-INP-(D)BAL-(D)TRP-PHE-APC-NH2, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF ALLERGAN GI CORP (US) 2021-08-19 US claimed
EP-3797795-A1 PREPARATION PROCESS OF ANTIBODY DRUG CONJUGATE INTERMEDIATE RemeGen, Ltd. (CN) 2021-03-31 EP claimed
US-20200172572-A1 PROCESS FOR THE LIQUID PHASE SYNTHESIS OF H-INP-(D)BAL-(D)TRP-PHE-APC-NH2, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF ALLERGAN GI CORP (US) 2020-06-04 US claimed
US-20200138968-A1 PROCESS FOR PREPARING INTERMEDIATE OF ANTIBODY DRUG CONJUGATE REMEGEN, LTD. (CN) 2020-05-07 US claimed
US-20170218015-A1 PROCESS FOR THE LIQUID PHASE SYNTHESIS OF H-INP-(D)BAL-(D)TRP-PHE-APC-NH2, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF ALLERGAN GI CORP. 2017-08-03 US claimed
EP-3114132-A1 PROCESS FOR THE LIQUID PHASE SYNTHESIS OF H-INP-(D)BAL-(D)TRP-PHE-APC-NH2, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF MOTUS THERAPEUTICS, INC. (US) 2017-01-11 EP claimed
WO-2015134567-A1 PROCESS FOR THE LIQUID PHASE SYNTHESIS OF H-INP-(D)BAL-(D)TRP-PHE-APC-NH2, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF RHYTHM PHARMACEUTICALS, INC. (US) 2015-09-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188118-A1 LIQUID PHASE PEPTIDE SYNTHESIS METHODS VIP, RNGTT, SSU72 ALDH1A1 3744/4885LMNA 1169/4885HPGD 2668/4885
US-20210253634-A1 PROCESS FOR THE LIQUID PHASE SYNTHESIS OF H-INP-(D)BAL-(D)TRP-PHE-APC-NH2, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF VIP, IAPP, PROKR1 ALDH1A1 3729/4885LMNA 1226/4885HPGD 601/4885
US-20200172572-A1 PROCESS FOR THE LIQUID PHASE SYNTHESIS OF H-INP-(D)BAL-(D)TRP-PHE-APC-NH2, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF VIP, IAPP, PROKR1 ALDH1A1 3729/4885LMNA 1226/4885HPGD 601/4885
US-20170218015-A1 PROCESS FOR THE LIQUID PHASE SYNTHESIS OF H-INP-(D)BAL-(D)TRP-PHE-APC-NH2, AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF VIP, IAPP, PROKR1 ALDH1A1 3729/4885LMNA 1226/4885HPGD 601/4885
US-20200138968-A1 PROCESS FOR PREPARING INTERMEDIATE OF ANTIBODY DRUG CONJUGATE MMAB, BTD, MGAM ALDH1A1 440/4885LMNA 3244/4885HPGD 3517/4885
US-20260001909-A1 Method for Preparing a Peptide With CCK Receptor Modulatory Activity CCKAR, CCKBR, VIP ALDH1A1 4641/4885LMNA 2515/4885HPGD 2682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.