Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMPD1 | P17405 | 6/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445183 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDSMPD1LTB4RTHRA | |
| SCHEMBL10339986 | 0.84 | NPC1 (0.55) | ALDH1A1HPGDSMPD1PLA2G4BTP53 | |
| SCHEMBL13790358 | 0.84 | LTB4R (0.61) | ALDH1A1HPGDSMPD1LTB4RTHRA | |
| SCHEMBL1579372 | 0.82 | ALDH1A1 (0.54) | ALDH1A1HPGDSMPD1TSHR | |
| SCHEMBL9445384 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HPGDSMPD1LTB4RTHRA | |
| SCHEMBL4518941 | 0.82 | SMPD1 (0.61) | ALDH1A1HPGDSMPD1LTB4RTHRA | |
| SCHEMBL4529930 | 0.80 | LTB4R (0.63) | ALDH1A1HPGDSMPD1LTB4RPLA2G4B | |
| SCHEMBL6737583 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDSMPD1PLA2G4BTP53 | |
| SCHEMBL4524617 | 0.80 | SMPD1 (0.52) | ALDH1A1HPGDSMPD1LTB4RTHRA | |
| SCHEMBL1200986 | 0.79 | ALDH1A1 (0.69) | ALDH1A1HPGDSMPD1PLA2G4BPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176995-A1 | Soluble fullerene derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176995-A1 | Soluble fullerene derivatives | SOD1, EPCAM, NDUFV2 | ALDH1A1 1019/4885HPGD 1452/4885SMPD1 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.