Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4533106 | 0.88 | NPBWR1 (0.51) | NPBWR1MCHR1ALDH1A1LMNAKDM4E | |
| SCHEMBL28128093 | 0.79 | NPBWR1 (0.51) | NPBWR1MCHR1ALDH1A1LMNAKDM4E | |
| SCHEMBL30402470 | 0.78 | HSD17B10 (0.55) | ALDH1A1LMNAKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL30799252 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL21996063 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6814914 | 0.78 | NPBWR1 (0.47) | NPBWR1MCHR1ALDH1A1LMNAKDM4E | |
| SCHEMBL22624766 | 0.76 | NPBWR1 (0.63) | NPBWR1MCHR1ALDH1A1LMNAKDM4E | |
| SCHEMBL4531959 | 0.76 | NPBWR1 (0.57) | NPBWR1MCHR1ALDH1A1KDM4EPOLB | |
| SCHEMBL1039759 | 0.76 | BCHE (0.50) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL2635104 | 0.74 | POLB (0.50) | ALDH1A1POLBGRIN2BSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | PLE PATRICK | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | AQP3, AQP1, F12 | NPBWR1 2103/4885MCHR1 1254/4885ALDH1A1 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.