Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GALR1 | P47211 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747047 | 0.85 | SDHB (0.50) | NPC1RAB9A | |
| SCHEMBL124262 | 0.83 | CA12 (0.50) | TP53POLBHPGDNPC1RAB9A | |
| Urethane SCHEMBL4538739 | 0.80 | PDE4B (0.47) | KDM4EALDH1A1MAPT | |
| SCHEMBL29617015 | 0.80 | TP53 (0.62) | TP53POLBHPGDNPC1RAB9A | |
| Urethane SCHEMBL4535005 | 0.79 | CSNK1D (0.45) | TP53HPGDKDM4EALDH1A1MAPT | |
| Urethane SCHEMBL4530068 | 0.79 | FOS (0.40) | TP53HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9874042 | 0.79 | KMO (0.51) | HPGDNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9340148 | 0.79 | ALDH1A1 (0.39) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL391755 | 0.78 | MAPK1 (0.38) | TP53POLBHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9874488 | 0.78 | TTR (0.47) | TP53NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064959-A | Photoinitiators | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |