Urethane

Urethane

SCHEMBL4538739

CCOC(N)=O.Clc1cccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)c1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 7/20 0.47
CYP2C19 P33261 2/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 2/20 0.46
TRPM8 Q7Z2W7 1/20 0.46
XPO1 O14980 1/20 0.45
KCNH2 Q12809 1/20 0.44
GABRA2 P47869 1/20 0.42
GABRB2 P47870 1/20 0.42
JAK2 O60674 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
JAK3 P52333 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
PDE4D Q08499 3/20 0.40
GRM5 P41594 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL4535005 0.87 CSNK1D (0.45) CYP2C19MAPTTRPM8XPO1JAK2
Urethane SCHEMBL4530068 0.87 FOS (0.40) MAPTL3MBTL1GRM5KDM4EALDH1A1
SCHEMBL394049 0.85 MAPT (0.48) PDE4BCYP2C19CYP3A4MAPTTRPM8
SCHEMBL1048783 0.80 IDO1 (0.46) PDE4BMAPTXPO1L3MBTL1KDM4E
SCHEMBL9873206 0.80 TP53 (0.48) MAPTKDM4EALDH1A1
SCHEMBL307863 0.77 IDO1 (0.46) PDE4BMAPTXPO1L3MBTL1KDM4E
Urethane SCHEMBL4535413 0.75 KDM4E (0.40) MAPTL3MBTL1CYP1A2KDM4EALDH1A1
SCHEMBL391755 0.74 MAPK1 (0.38) CYP2C19MAPTL3MBTL1CYP1A2CYP2C9
SCHEMBL9874488 0.74 TTR (0.47) CYP2C19CYP3A4MAPTCYP1A2CYP2C9
SCHEMBL9874485 0.74 TTR (0.47) CYP2C19CYP3A4MAPTCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7575837-B2 Colored curable composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2009-08-18 US disclosed
US-20060257762-A1 Colored curable composition, color filter and method for producing the same FUJI PHOTO FILM CO., LTD. 2006-11-16 US disclosed