Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29805281 | 1.00 | CSNK2A1 (0.39) | CSNK2A1PARP1MAPTDYRK1APRKCI | |
| SCHEMBL7032602 | 0.79 | PRKCI (0.41) | CSNK2A1PARP1MAPTDYRK1APRKCI | |
| SCHEMBL4908126 | 0.79 | CSNK2A1 (0.37) | CSNK2A1PARP1MAPTDYRK1APRKCI | |
| SCHEMBL18554530 | 0.79 | CSNK2A1 (0.37) | CSNK2A1PARP1MAPTDYRK1APRKCI | |
| SCHEMBL7348969 | 0.79 | PARP1 (0.37) | CSNK2A1PARP1MAPTDYRK1APRKCI | |
| SCHEMBL1374558 | 0.78 | PRKCI (0.44) | CSNK2A1PARP1MAPTDYRK1APRKCI | |
| SCHEMBL9738912 | 0.77 | LMNA (0.45) | PARP1MAPTDYRK1AALDH1A1KDM4E | |
| Naphthalene SCHEMBL9738334 | 0.76 | LMNA (0.44) | PARP1MAPTDYRK1AALDH1A1KDM4E | |
| SCHEMBL23841481 | 0.75 | PARP1 (0.34) | CSNK2A1PARP1MAPTDYRK1APRKCI | |
| SCHEMBL20889995 | 0.75 | CSNK2A1 (0.34) | CSNK2A1PARP1MAPTDYRK1APRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110191882-B | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 株式会社大熊制药 | 2022-09-13 | — | — | CN | disclosed |
| US-10981917-B2 | Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-04-20 | — | — | US | disclosed |
| US-8211590-B2 | Proton conducting material, and electrode and fuel cell using the same | PANASONIC CORPORATION (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20090017356-A1 | PROTON CONDUCTING MATERIAL, AND ELECTRODE AND FUEL CELL USING THE SAME | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2009-01-15 | — | — | US | disclosed |
| US-3988155-A | CYANINE SENSITIZING DYES | FUJI PHOTO FILM CO., LTD. (JA) | 1976-10-26 | — | — | US | disclosed |
| US-3985563-A | Silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981917-B2 | Heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same | RNASE1, AARS1, DHPS | CSNK2A1 1622/4885PARP1 381/4885MAPT 3729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.