SCHEMBL453533

SCHEMBL453533

FC(F)(F)C(=Cc1ccccc1)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C1 Q04828 1/20 0.40
ESR1 P03372 1/20 0.40
CES1 P23141 1/20 0.39
TP53 P04637 1/20 0.39
HTT P42858 1/20 0.38
FBP1 P09467 3/20 0.38
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
PRMT1 Q99873 1/20 0.36
MAOB P27338 1/20 0.36
CYP2A6 P11509 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31464217 0.98 ALDH1A1 (0.40) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL7031297 0.80 ALDH1A1 (0.41) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL17836918 0.78 ALDH1A1 (0.45) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL17836916 0.78 ALDH1A1 (0.45) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL10416173 0.76 FBP1 (0.44) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL9227444 0.76 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL9227437 0.76 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL10416172 0.76 FBP1 (0.44) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL31195612 0.76 ALDH1A1 (0.39) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL4995920 0.75 ALDH1A1 (0.46) ALDH1A1TSHRAKR1C3AKR1C1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119819370-A Preparation method of photocatalytic degradation material for treating acid chrome blue K sewage 北方工业大学 2025-04-15 CN claimed
CN-119819370-B Preparation method of photocatalytic degradation material for treating acid chrome blue K sewage 北方工业大学 2025-10-03 CN disclosed
CN-119819370-A Preparation method of photocatalytic degradation material for treating acid chrome blue K sewage 北方工业大学 2025-04-15 CN disclosed
CN-119819370-A Preparation method of photocatalytic degradation material for treating acid chrome blue K sewage 北方工业大学 2025-04-15 CN disclosed
US-20240124632-A1 Method for Producing Fluorine-Containing Polymer and Composition CENTRAL GLASS COMPANY, LIMITED (JP) 2024-04-18 US disclosed
US-20240043593-A1 Fluorine-Containing Polymer CENTRAL GLASS COMPANY, LIMITED (JP) 2024-02-08 US disclosed
CN-116848162-A Fluorine-containing polymer 中央硝子株式会社 2023-10-03 CN disclosed
CN-116694256-A Special resin adhesive for vehicle-gauge-level power soft-package tab and preparation method thereof 浙江文壹先端新材料有限公司 2023-09-05 CN disclosed
CN-112585113-B Process for distillative purification of fluorine-containing polymerizable monomers 中央硝子株式会社 2023-08-22 CN disclosed
CN-116615410-A Method for producing fluorine-containing polymer and composition 中央硝子株式会社 2023-08-18 CN disclosed
US-8663903-B2 Top coating composition CENTRAL GLASS COMPANY, LIMITED (JP) 2014-03-04 US disclosed
US-8592508-B2 Top coat composition CENTRAL GLASS COMPANY, LIMITED (JP) 2013-11-26 US disclosed
US-20130216960-A1 Water Repellent Additive for Immersion Resist CENTRAL GLASS COMPANY, LIMITED (JP) 2013-08-22 US disclosed
US-20130177848-A1 Polymer, Resist Material Containing Same, and Method for Forming Pattern Using Same CENTRAL GLASS COMPANY LIMITED (JP) 2013-07-11 US disclosed
US-20120077126-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer Compound, Resist Composition, Top Coat Composition And Pattern Formation Method CENTRAL GLASS COMPANY, LIMITED (JP) 2012-03-29 US disclosed
US-20120064459-A1 Water Repellent Additive for Immersion Resist CENTRAL GLASS COMPANY, LIMITED (JP) 2012-03-15 US disclosed
US-20120040294-A1 Top Coating Composition CENTRAL GLASS COMPANY, LIMITED (JP) 2012-02-16 US disclosed
US-20110245395-A1 Top Coat Composition CENTRAL GLASS COMPANY, LIMITED 2011-10-06 US disclosed
US-20110244188-A1 Polymerizable Fluoromonomer, Fluoropolymer, Resist Material, and Method of Pattern Formation Central Glass Company , Limited (JP) 2011-10-06 US disclosed
WO-1998000750-A1 PROCESS FOR PRODUCING LIQUID CRYSTAL ALIGNMENT LAYER AND LIQUID CRYSTAL DISPLAY DEVICE WITH THE USE OF THE SAME HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO. KG (DE) 1998-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110244188-A1 Polymerizable Fluoromonomer, Fluoropolymer, Resist Material, and Method of Pattern Formation AFF1, FRG1, AFF2 ALDH1A1 2056/4885TSHR 2566/4885AKR1C3 3061/4885
US-20120077126-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer Compound, Resist Composition, Top Coat Composition And Pattern Formation Method FRG1, AFF2, FBXL19 ALDH1A1 4430/4885TSHR 2270/4885AKR1C3 4079/4885
US-20240124632-A1 Method for Producing Fluorine-Containing Polymer and Composition PFAS, AFF2, AFF1 ALDH1A1 865/4885TSHR 552/4885AKR1C3 868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.