SCHEMBL4535883

SCHEMBL4535883

CC(Cl)Nc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MAPT P10636 1/20 0.31
CNR1 P21554 1/20 0.31
IDH1 O75874 1/20 0.30
NR4A2 P43354 1/20 0.30
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4535465 0.85
SCHEMBL4565200 0.78 KDM4E (0.31) MAPT
SCHEMBL482607 0.75 RAB9A (0.33) NPC1RAB9A
SCHEMBL4578727 0.75 NPC1 (0.33) NPC1RAB9A
SCHEMBL2403397 0.74 RAB9A (0.43) NPC1RAB9AMAPT
SCHEMBL14039148 0.72 RAB9A (0.42) NPC1RAB9AMAPT
SCHEMBL391621 0.72 IDH1 (0.46) MAPTIDH1
SCHEMBL4538734 0.71 ALDH1A1 (0.48) MAPT
SCHEMBL389280 0.70 LMNA (0.42) RAB9AMAPT
SCHEMBL482998 0.69 L3MBTL1 (0.39) NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7521158-B2 Negative dye-containing curable composition, color filter and method of producing the same FUJIFILM CORPORATION (JP) 2009-04-21 US disclosed
US-20060051685-A1 Negative dye-containing curable composition, color filter and method of producing the same FUJI PHOTO FILM CO., LTD. 2006-03-09 US disclosed