Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.54 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ATIC | P31939 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.43 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535887 | 1.00 | POLB (0.59) | POLBCYP2D6PHLPP2RPS6KA3LMNA | |
| SCHEMBL29596405 | 0.86 | POLB (0.56) | POLBCYP2D6PHLPP2RPS6KA3LMNA | |
| SCHEMBL4842357 | 0.86 | POLB (0.56) | POLBCYP2D6PHLPP2RPS6KA3LMNA | |
| SCHEMBL28560987 | 0.82 | POLB (0.83) | POLBCYP2D6PHLPP2RPS6KA3LMNA | |
| SCHEMBL18624977 | 0.82 | POLB (0.83) | POLBCYP2D6PHLPP2RPS6KA3LMNA | |
| SCHEMBL25027696 | 0.80 | RPS6KA3 (0.49) | POLBCYP2D6PHLPP2RPS6KA3LMNA | |
| SCHEMBL9099069 | 0.79 | RPS6KA3 (0.55) | POLBCYP2D6PHLPP2RPS6KA3LMNA | |
| SCHEMBL4842755 | 0.79 | RPS6KA3 (0.55) | POLBCYP2D6PHLPP2RPS6KA3LMNA | |
| SCHEMBL2171353 | 0.79 | LMNA (0.74) | POLBCYP2D6PHLPP2RPS6KA3LMNA | |
| SCHEMBL4808253 | 0.79 | LMNA (0.74) | POLBCYP2D6PHLPP2RPS6KA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618726-A | DYE HAVING LIGNIN-LIKE SUBSTITUTION PATTERN AND A MICROBE CAPABLE OF PRODUCING EXTRACELLULAR PEROXIDASE | IDAHO RESEARCH FOUNDATION, INC. (US) | 1997-04-08 | — | — | US | claimed |
| US-9645153-B2 | Labeling reagents and methods of their use | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-20150355186-A1 | Labeling Reagents and Methods of Their Use | INVITROGEN CORPORATION | 2015-12-10 | — | — | US | disclosed |
| US-9140706-B2 | Labeling reagents and methods of their use | Life Technologies Corporation (US) | 2015-09-22 | — | — | US | disclosed |
| US-20130337536-A1 | Labeling Reagents and Methods of Their Use | Life Technologies Corporation (US) | 2013-12-19 | — | — | US | disclosed |
| US-8586743-B2 | Labeling reagents and methods of their use | Life Technologies Corporation (US) | 2013-11-19 | — | — | US | disclosed |
| US-20090004753-A1 | LABELING REAGENTS AND METHODS OF THEIR USE | INVITROGEN CORPORATION (US) | 2009-01-01 | — | — | US | disclosed |
| WO-2006114616-A1 | ENGINEERED PEROXIDASES WITH VERATRYL ALCOHOL OXIDASE ACTIVITY | UNIVERSITY OF SUSSEX (GB) | 2006-11-02 | — | — | WO | disclosed |
| US-5618726-A | DYE HAVING LIGNIN-LIKE SUBSTITUTION PATTERN AND A MICROBE CAPABLE OF PRODUCING EXTRACELLULAR PEROXIDASE | IDAHO RESEARCH FOUNDATION, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| US-5486214-A | MONO OR DISAZO DYES, LIGNIN PEROXIDASE AND VERATRYL ALCOHOL MIXTURE FOR DEGRADATION OF DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1992017550-A1 | BIODEGRADABLE AZO DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1992-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150355186-A1 | Labeling Reagents and Methods of Their Use | GUSB, CES2, MRPL21 | POLB 1408/4885CYP2D6 180/4885PHLPP2 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.