Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 known ✓ | P35354 | 2/20 | 0.39 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.39 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.41 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535887 | 0.86 | POLB (0.59) | POLBCYP2D6PHLPP2RPS6KA3MEN1 | |
| SCHEMBL4535890 | 0.86 | POLB (0.59) | POLBCYP2D6PHLPP2RPS6KA3MEN1 | |
| SCHEMBL4842357 | 0.80 | POLB (0.56) | POLBCYP2D6PHLPP2RPS6KA3KMT2A | |
| SCHEMBL28560987 | 0.80 | POLB (0.83) | POLBCYP2D6PHLPP2RPS6KA3MEN1 | |
| SCHEMBL18624977 | 0.80 | POLB (0.83) | POLBCYP2D6PHLPP2RPS6KA3MEN1 | |
| SCHEMBL4842755 | 0.73 | RPS6KA3 (0.55) | POLBCYP2D6PHLPP2RPS6KA3MEN1 | |
| SCHEMBL9099069 | 0.73 | RPS6KA3 (0.55) | POLBCYP2D6PHLPP2RPS6KA3MEN1 | |
| SCHEMBL8843749 | 0.72 | PHLPP2 (0.75) | POLBCYP2D6PHLPP2RPS6KA3BRD4 | |
| SCHEMBL8843743 | 0.72 | PHLPP2 (0.75) | POLBCYP2D6PHLPP2RPS6KA3BRD4 | |
| SCHEMBL408153 | 0.72 | POLB (1.00) | POLBCYP2D6PHLPP2RPS6KA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4145164-B1 | COUPLING DEVICE FOR NMR FLOW CELL FOR MAGNETIC FIELD INDEPENDENT ALIGNMENT AND NMR SPECTROMETER | BRUKER SWITZERLAND AG (CH) | 2023-11-15 | — | — | EP | claimed |
| CN-112634446-B | Multi-engine three-dimensional scene data conversion method based on space-time consistency | 北方信息控制研究院集团有限公司 | 2023-09-26 | — | — | CN | claimed |
| EP-4145164-A1 | COUPLING DEVICE FOR NMR FLOW CELL FOR MAGNETIC FIELD INDEPENDENT ALIGNMENT AND NMR SPECTROMETER | Bruker Switzerland AG (CH) | 2023-03-08 | — | — | EP | claimed |
| CN-112098958-B | Radar clutter prediction method based on digital map and meteorological hydrological information | 中国电波传播研究所（中国电子科技集团公司第二十二研究所） | 2022-04-26 | — | — | CN | claimed |
| EP-4713342-A2 | SYSTEMS AND METHODS FOR REGULATING TARGET GENES | Epicrispr Biotechnologies, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| EP-4703990-A1 | METHOD OF MINING BEHAVIORAL PATTERNS FOR CONFORMANCE DIAGNOSTICS | Celonis SE (DE) | 2026-03-04 | — | — | EP | disclosed |
| EP-4601699-A1 | LIPID NANOPARTICLE FORMULATIONS FOR MRNA DELIVERY TO LANGERHANS CELLS | Cutanos GmbH (AT) | 2025-08-20 | — | — | EP | disclosed |
| CN-119810668-A | SAR image target detection method, device, equipment and medium based on cross-sensor | 中国人民解放军国防科技大学 | 2025-04-11 | — | — | CN | disclosed |
| US-12173111-B2 | Composition comprising polyesters for additive manufacturing | EVONIK OPERATIONS GMBH (DE) | 2024-12-24 | — | — | US | disclosed |
| CN-119107269-A | Underwater image restoration method based on self-adaptive brightness improvement and local image scattering | 安徽大学 | 2024-12-10 | — | — | CN | disclosed |
| WO-2024238661-A2 | SYSTEMS AND METHODS FOR REGULATING TARGET GENES | EPICRISPR BIOTECHNOLOGIES, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| CN-114549901-B | Multi-network combined auxiliary generation type knowledge distillation method | 杭州电子科技大学 | 2024-05-14 | — | — | CN | disclosed |
| EP-4076959-B1 | ADDITIVE MANUFACTURING PROCESS WITH A COMPOSITION COMPRISING POLYESTERS | EVONIK OPERATIONS GMBH (DE) | 2023-09-27 | — | — | EP | disclosed |
| CN-115943049-A | Method of making an additive using a composition comprising a polyester | 赢创运营有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-4145164-A1 | COUPLING DEVICE FOR NMR FLOW CELL FOR MAGNETIC FIELD INDEPENDENT ALIGNMENT AND NMR SPECTROMETER | Bruker Switzerland AG (CH) | 2023-03-08 | — | — | EP | disclosed |
| US-20220403093-A1 | COMPOSITION COMPRISING POLYESTERS FOR ADDITIVE MANUFACTURING | EVONIK OPERATIONS GMBH (DE) | 2022-12-22 | — | — | US | disclosed |
| EP-4076959-A1 | ADDITIVE MANUFACTURING PROCESS WITH A COMPOSITION COMPRISING POLYESTERS | Evonik Operations GmbH (DE) | 2022-10-26 | — | — | EP | disclosed |
| CN-114565081-A | End-to-end no-data antagonism knowledge extraction method based on graph structure data | 北京邮电大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-114549901-A | Multi-network joint auxiliary generation type knowledge distillation method | 杭州电子科技大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-112098958-B | Radar clutter prediction method based on digital map and meteorological hydrological information | 中国电波传播研究所（中国电子科技集团公司第二十二研究所） | 2022-04-26 | — | — | CN | disclosed |