SCHEMBL4535971

SCHEMBL4535971

CC(C)Cc1ccc(CCOCCc2ccc(CC(C)C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.42
PTGS1 P23219 3/20 0.42
CXCR1 P25024 3/20 0.42
CXCR2 P25025 3/20 0.42
LMNA P02545 2/20 0.42
CYP2C9 P11712 2/20 0.42
AKR1C3 P42330 2/20 0.42
ALB P02768 1/20 0.42
ESR1 P03372 1/20 0.42
ALOX5 P09917 1/20 0.42
RARB P10826 1/20 0.42
ADRB3 P13945 1/20 0.42
NFKB1 P19838 1/20 0.42
HTR2A P28223 1/20 0.42
NR1I3 Q14994 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
CXCL8 P10145 1/20 0.42
TSHR P16473 1/20 0.42
AKR1C2 P52895 1/20 0.42
BLM P54132 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8603942 0.84 NR3C1 (0.44) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL9176049 0.83 PTGS1 (0.50) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL1131597 0.80 PTGS1 (0.56) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL10794970 0.78 GPR84 (0.42) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL19771037 0.78 KCNH2 (0.37) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL25443761 0.77 PTGS1 (0.42) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL2362990 0.77 IDO1 (0.52) LMNA
SCHEMBL5174938 0.77 PTGS1 (0.54) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL9161078 0.77 LMNA (0.46) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL4048513 0.77 ALDH1A1 (0.44) PTGS2PTGS1CXCR1CXCR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009059944-A1 ELECTROCHEMICAL METHOD FOR PRODUCING BENZALDEHYDE DIMETHYL ACETYLENE BASF SE (DE) 2009-05-14 WO disclosed