SCHEMBL4536023

SCHEMBL4536023

CCC(CCCNC(C)C)[SiH](O)O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CACNA2D1 P54289 1/20 0.30
ADRB2 P07550 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4532157 0.79 KISS1R (0.36)
SCHEMBL20931126 0.72 CACNA2D1 (0.34) CACNA2D1ADRB2
SCHEMBL14980541 0.72 ALDH1A1 (0.39) CACNA2D1ADRB2
SCHEMBL4531326 0.71 OPRM1 (0.44)
SCHEMBL4529624 0.70 SPHK1 (0.31)
SCHEMBL4524434 0.69 OPRM1 (0.48)
SCHEMBL6279880 0.68 LMNA (0.41) CACNA2D1ADRB2
SCHEMBL16062564 0.68 LMNA (0.41) CACNA2D1ADRB2
SCHEMBL4525902 0.67 CYP2D6 (0.32)
SCHEMBL7226656 0.67 TSHR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed