SCHEMBL4536089

SCHEMBL4536089

O=C(Cl)OC(F)(F)C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11597897 1.00 THRB (0.33) THRB
SCHEMBL15157148 0.77 THRB (0.31) THRB
SCHEMBL5480123 0.77 THRB (0.31) THRB
SCHEMBL692689 0.77 THRB (0.31) THRB
SCHEMBL15153787 0.76 ALDH1A1 (0.31)
SCHEMBL690711 0.76 ALDH1A1 (0.31)
SCHEMBL1435487 0.76 ALDH1A1 (0.31)
SCHEMBL16223137 0.75
SCHEMBL2902322 0.73 LMNA (0.32)
SCHEMBL8401587 0.73 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012064417-A1 URETHANE AND UREA FLUOROSURFACTANTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-18 WO disclosed