Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21168596 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HPGDKMT2ATDP1MEN1 | |
| SCHEMBL17532418 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HPGDKMT2ATDP1MEN1 | |
| SCHEMBL9179752 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2ATDP1MEN1 | |
| SCHEMBL5427844 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2ATDP1MEN1 | |
| SCHEMBL9181557 | 0.81 | HTT (0.54) | ALDH1A1HPGDKMT2ATDP1MEN1 | |
| SCHEMBL9179747 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2ATDP1MEN1 | |
| SCHEMBL13606476 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1HPGDKMT2ATDP1MEN1 | |
| SCHEMBL9181566 | 0.81 | HTT (0.54) | ALDH1A1HPGDKMT2ATDP1MEN1 | |
| SCHEMBL11860195 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2ATDP1MEN1 | |
| SCHEMBL9513818 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312344-A1 | ARYLPIPERAZINE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-12-17 | — | — | US | disclosed |
| US-20070219216-A1 | 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2007-09-20 | — | — | US | disclosed |
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |
| EP-0940390-B1 | [6-(Substituted-methyl)-3-cyclohexenyl]formamide derivative, hair growth promoter and external composition for skin | SHISEIDO CO LTD (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-6174885-B1 | IMPROVEMENT OR PREVENTION OF HAIR LOSS IN MAMMALS AND, IN PARTICULAR, IN HUMAN | SHISEIDO CO., LTD. (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0940390-A1 | 6- (Substituted-methyl) -3- cyclohexenyl formamide derivative, hair growth promoter and external composition for skin | SHISEIDO COMPANY LIMITED (JP) | 1999-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219216-A1 | 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists | ADRA1D, ADRA1A, ADRB1 | ALDH1A1 51/4885HPGD 212/4885KMT2A 3012/4885 |
| US-20090312344-A1 | ARYLPIPERAZINE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | ADRA1D, ADRB1, ADRA1A | ALDH1A1 50/4885HPGD 131/4885KMT2A 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.