Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN7A | Q01118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541853 | 0.81 | SCN7A (0.44) | SCN7AMEN1MAPTKMT2ASIGMAR1 | |
| SCHEMBL4539823 | 0.76 | NPC1 (0.40) | LTA4HNPC1TSHRRAB9A | |
| SCHEMBL16621374 | 0.67 | SCN7A (0.58) | SCN7AMEN1MAPTKMT2ASIGMAR1 | |
| SCHEMBL4536226 | 0.67 | SCN7A (0.58) | SCN7AMEN1MAPTKMT2ASIGMAR1 | |
| SCHEMBL622368 | 0.66 | FGFR3 (0.49) | MEN1MAPTKMT2ALTA4H | |
| SCHEMBL16621435 | 0.66 | SCN7A (0.60) | SCN7AMEN1MAPTKMT2ASIGMAR1 | |
| SCHEMBL28750189 | 0.66 | ALDH1A1 (0.48) | MAPTSIGMAR1NPC1TSHR | |
| SCHEMBL15661893 | 0.65 | LTA4H (0.43) | SCN7AMEN1MAPTKMT2ASIGMAR1 | |
| SCHEMBL15661237 | 0.65 | FGFR3 (0.40) | SCN7AMEN1MAPTKMT2ASIGMAR1 | |
| SCHEMBL15661371 | 0.65 | MEN1 (0.40) | SCN7AMEN1MAPTKMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | MSD K.K. (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1939194-A1 | BICYCLIC AROMATIC SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | PYCR1, CHRM1, MTR | SCN7A 4125/4885MEN1 183/4885MAPT 4595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.