Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582711 | 0.93 | REN (0.39) | REN | |
| SCHEMBL4584771 | 0.93 | REN (0.38) | RENCYP3A4 | |
| SCHEMBL4583042 | 0.92 | REN (0.37) | RENCYP3A4 | |
| SCHEMBL4526400 | 0.91 | REN (0.39) | RENCYP3A4 | |
| SCHEMBL4583869 | 0.91 | REN (0.37) | RENCYP3A4 | |
| SCHEMBL4583266 | 0.91 | REN (0.37) | RENCYP3A4 | |
| SCHEMBL4582659 | 0.90 | REN (0.36) | RENCYP3A4 | |
| SCHEMBL4584098 | 0.88 | REN (0.46) | RENCYP3A4 | |
| SCHEMBL4582823 | 0.85 | REN (0.38) | RENCYP3A4 | |
| SCHEMBL3074966 | 0.84 | REN (0.42) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325947-A1 | NITRATE ESTERS OF PIPERIDINES | NOVARTIS AG (CH) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325947-A1 | NITRATE ESTERS OF PIPERIDINES | NOS2, NOS1, NOS3 | REN 29/4885CYP3A4 674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.