Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537967 | 0.94 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TSHRRECQLLMNA | |
| SCHEMBL4542202 | 0.90 | KMT2A (0.49) | ALDH1A1L3MBTL1TSHRKMT2APOLB | |
| SCHEMBL4539894 | 0.89 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL4537356 | 0.87 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1RECQLLMNAMEN1 | |
| SCHEMBL4535924 | 0.83 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1EPHX2MEN1KMT2A | |
| SCHEMBL4533514 | 0.83 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1EPHX2MEN1KMT2A | |
| SCHEMBL4539044 | 0.83 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL4535742 | 0.83 | NPC1 (0.52) | ALDH1A1L3MBTL1TSHRLMNAEPHX2 | |
| SCHEMBL4542841 | 0.82 | RAB9A (0.55) | ALDH1A1TSHRGAATP53RAB9A | |
| SCHEMBL4537525 | 0.82 | EPHX2 (0.50) | ALDH1A1L3MBTL1EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |