Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16175119 | 0.79 | APLNR (0.35) | CA2 | |
| SCHEMBL1155853 | 0.76 | AKR1C3 (0.33) | — | |
| SCHEMBL1155855 | 0.76 | AKR1C3 (0.33) | — | |
| SCHEMBL13269845 | 0.74 | CA2 (0.37) | CA2 | |
| SCHEMBL9933938 | 0.73 | LMNA (0.32) | — | |
| SCHEMBL9933942 | 0.73 | LMNA (0.32) | — | |
| SCHEMBL6342245 | 0.71 | CYP3A4 (0.34) | — | |
| SCHEMBL16175118 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL5732344 | 0.68 | CA2 (0.39) | CA2 | |
| SCHEMBL6333201 | 0.68 | MAPT (0.36) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123870-A1 | HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK & CO., INC. (US) | 2009-10-08 | — | — | WO | disclosed |