Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16586846 | 0.86 | CYP2C9 (0.50) | KMT2ATSHRALDH1A1CYP2C9HTT | |
| SCHEMBL7714538 | 0.75 | KMT2A (0.48) | KMT2ALMNATSHRKDM4EL3MBTL1 | |
| SCHEMBL1495972 | 0.73 | KMT2A (0.47) | KMT2ALMNATSHRKDM4EL3MBTL1 | |
| SCHEMBL29421388 | 0.73 | LMNA (0.50) | KMT2ALMNATSHRKDM4EL3MBTL1 | |
| SCHEMBL6339486 | 0.71 | MAPT (0.48) | KMT2ALMNATSHRKDM4EL3MBTL1 | |
| SCHEMBL31728066 | 0.71 | LMNA (0.64) | KMT2ALMNATSHRKDM4EL3MBTL1 | |
| SCHEMBL14405125 | 0.69 | KMT2A (0.50) | KMT2ALMNAALDH1A1MAPTPOLB | |
| SCHEMBL12686069 | 0.69 | KMT2A (0.55) | KMT2ALMNATSHRKDM4EL3MBTL1 | |
| SCHEMBL14719759 | 0.69 | MMP2 (0.68) | KMT2ALMNATSHRALDH1A1GAA | |
| SCHEMBL10900999 | 0.68 | CYP2C9 (0.71) | KMT2AALDH1A1CYP2C9GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |