Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383735 | 0.89 | MMP2 (0.64) | MMP2CA1CA2PKMMAPT | |
| SCHEMBL25348950 | 0.88 | MMP2 (0.62) | MMP2CA1CA2PKMMAPT | |
| SCHEMBL7094393 | 0.86 | MMP2 (0.60) | MMP2CA1CA2PKMMAPT | |
| SCHEMBL6688886 | 0.81 | PKM (0.66) | MMP2PKMMAPTALDH1A1POLB | |
| SCHEMBL10178084 | 0.78 | HTR6 (0.54) | MMP2PKMMAPTALDH1A1POLB | |
| SCHEMBL2914477 | 0.77 | MMP2 (0.53) | MMP2CA1CA2PKMMAPT | |
| SCHEMBL29080002 | 0.77 | MMP2 (0.53) | MMP2CA1CA2PKMMAPT | |
| SCHEMBL1562072 | 0.77 | PARL (0.66) | MMP2CA1CA2PKMMAPT | |
| SCHEMBL4005331 | 0.75 | MMP2 (0.59) | MMP2CA1CA2PKMMAPT | |
| SCHEMBL12053364 | 0.75 | MEN1 (0.73) | PKMMAPTHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053565-A1 | SUBSTITUTED 3-PIPERIDONE COMPOUNDS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053565-A1 | SUBSTITUTED 3-PIPERIDONE COMPOUNDS | HTR3C, NPEPPS, RAP2C | MMP2 2735/4885CA1 4765/4885CA2 4545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.