Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714538 | 0.86 | KMT2A (0.48) | MAPTKDM4ELMNATSHRL3MBTL1 | |
| SCHEMBL5212025 | 0.83 | MAPT (0.36) | MAPTLMNAALDH1A1 | |
| SCHEMBL31259600 | 0.82 | CYP2C9 (0.48) | MAPTTSHRKMT2ATP53ALDH1A1 | |
| SCHEMBL6341415 | 0.81 | MEN1 (0.44) | MAPTKDM4ELMNATSHRL3MBTL1 | |
| SCHEMBL7543301 | 0.80 | GABRG2 (0.43) | LMNAKMT2AALDH1A1 | |
| SCHEMBL31259518 | 0.78 | MAPT (0.47) | MAPTKMT2ATP53POLBCYP2C9 | |
| SCHEMBL7544590 | 0.77 | RARA (0.41) | MAPTKDM4ELMNAL3MBTL1KMT2A | |
| SCHEMBL7547077 | 0.77 | ALDH1A1 (0.40) | MAPTKDM4ELMNAL3MBTL1KMT2A | |
| SCHEMBL5209508 | 0.77 | GABRG2 (0.37) | LMNAKMT2AALDH1A1 | |
| SCHEMBL5240927 | 0.75 | MAPT (0.36) | MAPTKDM4ELMNATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936602-B1 | Benzazepine derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-30 | — | — | US | disclosed |
| EP-1186604-A1 | BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-13 | — | — | EP | disclosed |