Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565326 | 0.83 | KDM4E (0.47) | CYP2D6CYP2C19ALDH1A1USP2MAPT | |
| SCHEMBL473687 | 0.76 | BCL2L1 (0.46) | ALDH1A1SMN1; SMN2MAPTTHRBKDM4E | |
| SCHEMBL4541593 | 0.75 | CMA1 (0.48) | ALDH1A1MAPTTHRBKDM4EPOLB | |
| SCHEMBL31314634 | 0.75 | CMA1 (0.48) | ALDH1A1MAPTTHRBKDM4EPOLB | |
| SCHEMBL487121 | 0.75 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2USP2MAPTTHRB | |
| Hydrochloric Acid SCHEMBL487123 | 0.75 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTTHRBKDM4E | |
| SCHEMBL14679114 | 0.74 | CYP2D6 (0.73) | HDAC8HDAC6CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14985633 | 0.72 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2USP2MAPTTHRB | |
| SCHEMBL50803 | 0.71 | CA12 (0.44) | ALDH1A1SMN1; SMN2MAPTKDM4EPOLB | |
| SCHEMBL29590299 | 0.71 | CA12 (0.44) | ALDH1A1SMN1; SMN2MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638027-B1 | LOW-EXTRACTABLE THIOXANTHONES | IGM RESINS ITALIA SRL (IT) | 2016-07-13 | — | — | EP | disclosed |
| US-8933142-B2 | Low-extractable thioxanthones | LAMBERTI SPA (IT) | 2015-01-13 | — | — | US | disclosed |
| EP-2638027-A1 | LOW-EXTRACTABLE THIOXANTHONES | Lamberti SpA (IT) | 2013-09-18 | — | — | EP | disclosed |
| US-20130237628-A1 | LOW-EXTRACTABLE THIOXANTHONES | IGM RESINS ITALIA S.R.L. (IT) | 2013-09-12 | — | — | US | disclosed |
| WO-2012062692-A1 | LOW-EXTRACTABLE THIOXANTHONES | LAMBERTI SPA (IT) | 2012-05-18 | — | — | WO | disclosed |