Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.71 |
| ▸ | DRD4 | P21917 | 3/20 | 0.68 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.63 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691440 | 0.95 | DRD4 (0.70) | ITGB3ITGA2BDRD4HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8690310 | 0.94 | DRD4 (0.68) | ITGB3ITGA2BDRD4HTR2AHTR2C | |
| SCHEMBL10901064 | 0.90 | ITGB3 (0.70) | ITGB3ITGA2BDRD4HTR7DRD2 | |
| SCHEMBL7364364 | 0.85 | DRD4 (0.59) | ITGB3ITGA2BDRD4HTR2AHTR2C | |
| SCHEMBL8744975 | 0.85 | ITGB3 (0.64) | ITGB3ITGA2BDRD4ALDH1A1SIGMAR1 | |
| SCHEMBL1066467 | 0.83 | HTR2A (0.72) | ITGB3ITGA2BDRD4HTR2AHTR2C | |
| SCHEMBL3320211 | 0.83 | DRD4 (0.74) | DRD4HTR2AHTR2CHTR2BHTR7 | |
| SCHEMBL10900437 | 0.82 | ADRA1D (0.62) | HDAC4HDAC1DRD2LMNAALDH1A1 | |
| SCHEMBL7459360 | 0.82 | HTR2A (0.71) | ITGB3ITGA2BDRD4HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL4653252 | 0.82 | HTR2A (0.71) | ITGB3ITGA2BDRD4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064569-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-05-18 | — | — | WO | disclosed |
| EP-0858453-A1 | 5-(ACETAMIDOMETHYL)-3-ARYLDIHYDROFURAN-2-ONE AND TETRAHYDROFURAN-2-ONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | AstraZeneca AB (SE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997014690-A1 | 5-(ACETAMIDOMETHYL)-3-ARYLDIHYDROFURAN-2-ONE AND TETRAHYDROFURAN-2-ONE DERIVATIVES WITH ANTIBIOTIC ACTIVITY | ZENECA LIMITED (GB) | 1997-04-24 | — | — | WO | disclosed |