Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536852 | 0.88 | HTR1A (0.52) | RAB9AHTR7 | |
| SCHEMBL4530970 | 0.87 | HTR7 (0.52) | RAB9AHTR7TMEM97 | |
| SCHEMBL4540631 | 0.86 | RAB9A (0.51) | RAB9APAX8HCRTR1HCRTR2 | |
| SCHEMBL4538143 | 0.86 | RAB9A (0.50) | RAB9AHCRTR1HCRTR2 | |
| SCHEMBL4537566 | 0.85 | RAB9A (0.57) | RAB9ANPC1 | |
| SCHEMBL4533331 | 0.85 | HTR1A (0.56) | RAB9AHTR7 | |
| SCHEMBL4537171 | 0.84 | RAB9A (0.51) | RAB9ANPC1PAX8 | |
| SCHEMBL4537004 | 0.84 | RAB9A (0.49) | RAB9APAX8 | |
| SCHEMBL4542351 | 0.84 | RAB9A (0.49) | RAB9ANPC1PAX8 | |
| SCHEMBL4539816 | 0.84 | RAB9A (0.60) | RAB9AHTR7TMEM97SIGMAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | claimed |