Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541860 | 0.97 | RAB9A (0.61) | RAB9A | |
| SCHEMBL4539055 | 0.89 | RAB9A (0.46) | RAB9A | |
| SCHEMBL4536845 | 0.89 | RAB9A (0.52) | RAB9ANPC1 | |
| SCHEMBL4535937 | 0.89 | PSEN1 (0.58) | RAB9AALDH1A1 | |
| SCHEMBL4535259 | 0.89 | RAB9A (0.55) | RAB9AALDH1A1 | |
| SCHEMBL4530970 | 0.89 | HTR7 (0.52) | RAB9ANPSR1 | |
| SCHEMBL4536852 | 0.88 | HTR1A (0.52) | RAB9A | |
| SCHEMBL4538143 | 0.88 | RAB9A (0.50) | RAB9AALDH1A1 | |
| SCHEMBL4538792 | 0.86 | PSEN1 (0.53) | RAB9A | |
| SCHEMBL4541156 | 0.86 | RAB9A (0.58) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | claimed |
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |