Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.49 |
| ▸ | RXRB | P28702 | 5/20 | 0.49 |
| ▸ | RXRG | P48443 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648904 | 0.84 | RXRA (0.41) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL6416192 | 0.82 | RXRA (0.44) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL11775628 | 0.80 | RXRA (0.49) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL9092770 | 0.78 | RXRA (0.53) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL8384554 | 0.76 | BCL2L1 (0.46) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL7066399 | 0.74 | PTPN1 (0.55) | RXRARXRBRXRGMEN1KMT2A | |
| SCHEMBL7985338 | 0.74 | KMT2A (0.54) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL942431 | 0.73 | NPC1 (0.47) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL8034169 | 0.73 | PTPN1 (0.50) | ALDH1A1MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL13868390 | 0.72 | ALDH1A1 (0.42) | RXRARXRBRXRGALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009121033-A2 | SUBSTITUTED NITROGEN HETEROCYCLES AND SYNTHESIS AND USES THEREOF | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2009-10-01 | — | — | WO | disclosed |