Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 19/20 | 0.73 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.67 |
| ▸ | HTR2C | P28335 | 4/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005317 | 0.84 | HTR7 (1.00) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL4380313 | 0.81 | HTR7 (0.76) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL4382987 | 0.79 | HTR7 (0.83) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL4378140 | 0.78 | HTR7 (0.69) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL7006872 | 0.78 | HTR7 (0.81) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL7011314 | 0.78 | HTR7 (1.00) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL7006812 | 0.78 | HTR7 (1.00) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL7012708 | 0.76 | HTR7 (0.67) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL4376845 | 0.75 | HTR7 (0.76) | HTR7ADRA1DADRA1AADRA1BHTR2C | |
| SCHEMBL7169972 | 0.73 | HTR7 (0.62) | HTR7ADRA1DADRA1AADRA1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1280781-B1 | 5-HT 7 RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-18 | — | — | EP | disclosed |