Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541362 | 0.85 | KMT2A (0.37) | L3MBTL3L3MBTL1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL25001758 | 0.78 | L3MBTL1 (0.39) | L3MBTL3L3MBTL1HRH3KMT2A | |
| SCHEMBL17308232 | 0.78 | KDM4E (0.41) | KMT2A | |
| SCHEMBL3159987 | 0.77 | HTR6 (0.41) | L3MBTL3L3MBTL1HRH3KHKHPGD | |
| SCHEMBL310984 | 0.76 | SIGMAR1 (0.38) | KHK | |
| SCHEMBL1993991 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL8487744 | 0.75 | SMYD3 (0.30) | — | |
| SCHEMBL2554838 | 0.75 | KMT2A (0.44) | L3MBTL3L3MBTL1HRH3KHKHPGD | |
| SCHEMBL4665502 | 0.75 | HPGD (0.33) | L3MBTL3L3MBTL1HRH3KHKHPGD | |
| SCHEMBL1479533 | 0.75 | KMT2A (0.42) | KHKKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071691-A2 | OXINDOLE DERIVATIVES AND THE USE THEREOF AS A MEDICATION | ABBOTT GMBH & CO. KG (DE) | 2009-06-11 | — | — | WO | disclosed |