Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4542986 | 0.91 | MEN1 (0.49) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4538837 | 0.91 | MAPK1 (0.46) | SMN1; SMN2MAPK1PDE2AEPHX2NR1H4 | |
| SCHEMBL4543630 | 0.89 | MEN1 (0.53) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4540440 | 0.85 | MAPK14 (0.48) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4544004 | 0.84 | MEN1 (0.67) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4540559 | 0.80 | MEN1 (0.51) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4538848 | 0.80 | SCN3A (0.47) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4543760 | 0.80 | PTGER4 (0.41) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4543960 | 0.79 | GRM5 (0.43) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4539918 | 0.78 | MAPT (0.49) | MEN1KMT2ASMN1; SMN2MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |