Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540339 | 0.83 | MEN1 (0.70) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4543579 | 0.82 | SMN1; SMN2 (0.55) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4540440 | 0.81 | MAPK14 (0.48) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4540280 | 0.81 | DGAT2 (0.44) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4542986 | 0.80 | MEN1 (0.49) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4541107 | 0.80 | MEN1 (0.49) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4543630 | 0.79 | MEN1 (0.53) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4538837 | 0.78 | MAPK1 (0.46) | NPSR1KDM4ECYP1A2CYP3A4GAA | |
| SCHEMBL4543701 | 0.78 | MEN1 (0.75) | MEN1KMT2APPARGNR2E3NCOR2 | |
| SCHEMBL4538115 | 0.78 | NPC1 (0.48) | MEN1KMT2APPARGNR2E3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |