Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.43 |
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506133 | 0.97 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2HIF1AMEN1KMT2A | |
| SCHEMBL9395351 | 0.88 | CYP3A4 (0.49) | CYP3A4SMN1; SMN2HIF1AMEN1KMT2A | |
| SCHEMBL14685191 | 0.82 | CYP3A4 (0.64) | CYP3A4SMN1; SMN2HIF1AMEN1KMT2A | |
| SCHEMBL29167471 | 0.79 | CYP3A4 (0.60) | CYP3A4SMN1; SMN2HIF1AMEN1KMT2A | |
| SCHEMBL9632640 | 0.79 | CYP3A4 (0.60) | CYP3A4SMN1; SMN2HIF1AMEN1KMT2A | |
| SCHEMBL28121417 | 0.79 | SMN1; SMN2 (0.65) | CYP3A4SMN1; SMN2HIF1AMEN1KMT2A | |
| SCHEMBL15737711 | 0.78 | CYP3A4 (0.59) | CYP3A4SMN1; SMN2HIF1AMEN1KMT2A | |
| Potassium Ion SCHEMBL4542314 | 0.77 | CYP3A4 (0.41) | CYP3A4SMN1; SMN2HIF1AMEN1KMT2A | |
| SCHEMBL8679414 | 0.77 | CYP3A4 (0.57) | CYP3A4SMN1; SMN2HIF1AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27231886 | 0.77 | SMN1; SMN2 (0.57) | CYP3A4SMN1; SMN2HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1332865-B1 | Method for producing biochemical analysis unit | FUJIFILM CORP (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-7531057-B2 | Method for producing biochemical analysis unit | FUJIFILM CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
| US-7368026-B2 | Biochemical analysis unit and method for producing thereof | FUJIFILM CORPORATION (JP) | 2008-05-06 | — | — | US | disclosed |
| EP-1333285-B1 | Biochemical analysis unit and method for producing thereof | FUJI PHOTO FILM CO LTD (JP) | 2005-03-30 | — | — | EP | disclosed |
| US-20030153070-A1 | Biochemical analysis unit and method for producing thereof | FUJI PHOTO FILM CO., LTD. | 2003-08-14 | — | — | US | disclosed |
| EP-1333285-A1 | Biochemical analysis unit and method for producing thereof | FUJI PHOTO FILM CO., LTD. (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-1332865-A1 | Method for producing biochemical analysis unit | FUJI PHOTO FILM CO., LTD. (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-20030143523-A1 | Method for producing biochemical analysis unit | FUJI PHOTO FILM CO., LTD. | 2003-07-31 | — | — | US | disclosed |